Evidence map›Paper›PMID 32093103›Full record

ReviewInternational journal of molecular sciences2020

Brain Metastases in Lung Cancers with Emerging Targetable Fusion Drivers.

Aaron C Tan, Malinda Itchins, Mustafa Khasraw

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 40 citations in OpenAlex.

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  17. Metastasis Inhibition.International journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Aaron C TanDivision of Medical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.ORCID 0000-0001-7292-1114
Malinda ItchinsDepartment of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Mustafa KhasrawThe Preston Robert Tisch Brain Tumor Center, Duke Cancer Institute, Duke University, Durham, NC 27708, USA.
Duke University · USNational Cancer Centre Singapore · SGThe University of Sydney · AU

Funding

International Association for the Study of Lung Cancer IASLC Fellowship 2018-2020
6 · The paper itself

Abstract

The management of non-small cell lung cancer (NSCLC) has transformed with the discovery of therapeutically tractable oncogenic drivers. In addition to activating driver mutations, gene fusions or rearrangements form a unique sub-class, with anaplastic lymphoma kinase (

Indexed as

Anaplastic Lymphoma KinaseAntineoplastic Combined Chemotherapy ProtocolsBlood-Brain BarrierBrain NeoplasmsCarcinoma, Non-Small-Cell LungErbB ReceptorsHumansLung NeoplasmsMolecular Targeted TherapyNeoplasm MetastasisNeuregulin-1Oncogene Proteins, FusionProtein-Tyrosine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-retReceptor, trkAALK protein, humanAnaplastic Lymphoma KinaseErbB ReceptorsNeuregulin-1NRG1 protein, humanNTRK1 protein, humanOncogene Proteins, FusionProtein-Tyrosine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-retReceptor, trkARET protein, humanROS1 protein, humanbrain metastasesfusion driversnon-small cell lung cancertargeted therapy

Identifiers

PMID32093103
PMCPMC7073114
OpenAlexW3007611778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.