Evidence map›Paper›PMID 32093077›Full record

Observational studyNutrients2020

Nutritional Intake Influences Zinc Levels in Preterm Newborns: An Observational Study.

Gianluca Terrin, Giovanni Boscarino, Maria Di Chiara, Silvia Iacobelli, Francesca Faccioli, Carla Greco, Elisa Onestà, Giulia Sabatini, Andrea Pietravalle, Salvatore Oliva and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Effect of enteral zinc supplementation on growth and neurodevelopment of preterm infants: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Pooled it
  2. The Comparison of Fresh and Dry Duckweed (Plants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Observational
  5. Feeding Approach to Optimizing Nutrition in Infants with Congenital Heart Disease.Journal of cardiovascular development and disease · 2025
    Review
  6. Article
  7. Tracing Zinc's Role in Preterm Infants' Health: A Narrative Review.Advances in nutrition (Bethesda, Md.) · 2024
    Review
  8. Article
  9. Is it time for a precision health approach to the management of newborn hyperbilirubinemia?Journal of perinatology : official journal of the California Perinatal Association · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Review
  18. Article
  19. Article
  20. Zinc levels in neonatal life influence long-term neurodevelopment.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Gianluca TerrinDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.ORCID 0000-0003-3541-2876
Giovanni BoscarinoDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Maria Di ChiaraDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Silvia IacobelliService de Néonatologie. Centre Hospitalier Universitaire Sud Réunion, BP 350, 97448 Saint-Pierre Cedex, La Réunion, France.
Francesca FaccioliDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Carla GrecoDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Elisa OnestàDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Giulia SabatiniDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Andrea PietravalleDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Salvatore OlivaDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Maria Giulia ContiDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Fabio NataleDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Mario De CurtisDepartment of Maternal and Child Health, University of Roma La Sapienza, 00161 Rome, Italy.
Sapienza University of Rome · ITCentre Hospitalier Universitaire de La Réunion · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Zinc is a key element for protein synthesis in preterm newborns. Early aggressive nutrition, promoting protein synthesis, may increase zinc consumption; (2) Methods: We performed a prospective observational study, to assess the relationship between early macronutrients intake and serum zinc levels, in preterm newborns with Gestational Age (GA) of 24-35 weeks, consecutively observed in Neonatal Intensive Care Unit (NICU). (3) Results: We enrolled 130 newborns (GA 31.5 ± 2.8). A significant negative correlation between serum zinc level at 28 days of life and energy (r -0.587,

Indexed as

Infant Nutritional Physiological PhenomenaParenteral NutritionDietary ProteinsEnergy IntakeFemaleGestational AgeHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalLinear ModelsMaleProspective StudiesZincDietary ProteinsZincenergy intakeparenteral nutritionprotein intakerefeeding syndromeVLBW

Identifiers

PMID32093077
PMCPMC7071515
OpenAlexW3006880095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.