Structural Analysis and Design of Chionodracine-Derived Peptides Using Circular Dichroism and Molecular Dynamics Simulations.

Stefano Borocci, Giulia Della Pelle, Francesca Ceccacci, Cristina Olivieri, Francesco Buonocore, Fernando Porcelli

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 45% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Stefano BorocciDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.

Giulia Della PelleDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.

Francesca CeccacciCNR-Institute for Biological Systems, Sede Secondaria di Roma-Meccanismi di Reazione, 00185 Rome, Italy.

Cristina OlivieriDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.

Francesco BuonocoreDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.

Fernando PorcelliDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.

Università degli Studi della Tuscia · ITInstitute for Biological SystemsUniversity of Minnesota · US

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca Departments of Excellence 2018

6 · The paper itself

Abstract

Antimicrobial peptides have been identified as one of the alternatives to the extensive use of common antibiotics as they show a broad spectrum of activity against human pathogens. Among these is Chionodracine (

Indexed as

Amino Acid SequenceAnimalsAnisotropyAnti-Bacterial AgentsAntimicrobial Cationic PeptidesCircular DichroismLipid BilayersMembranes, ArtificialMolecular Dynamics SimulationPerciformesPhosphatidylcholinesProtein Conformation, alpha-HelicalWater1-palmitoyl-2-oleoylphosphatidylcholineAnti-Bacterial AgentsAntimicrobial Cationic Peptideschionodracine, Chionodraco hamatusLipid BilayersMembranes, ArtificialPhosphatidylcholinesWaterantimicrobial peptideschionodracinescircular dichroismmolecular dynamicspeptide-membrane interaction

Identifiers

PMID32092980

DOI10.3390/ijms21041401

PMCPMC7073106

OpenAlexW3009013426

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.