Evidence map›Paper›PMID 32092956›Full record

ArticleMarine drugs2020

Bioactive Metabolites of Marine Origin Have Unusual Effects on Model Membrane Systems.

Martin Jakubec, Christian Totland, Frode Rise, Elahe Jafari Chamgordani, Britt Paulsen, Louis Maes, An Matheeussen, Lise-Lotte Gundersen, Øyvind Halskau

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Martin JakubecDepartment of Biological Sciences, University of Bergen, Thormøhlensgate 55, NO-5006 Bergen, Norway.ORCID 0000-0002-6180-6900
Christian TotlandDepartment of Environmental Chemistry, Norwegian Geotechnical Institute, Sognsveien 72, 0855 Oslo, Norway.ORCID 0000-0002-1457-9012
Frode RiseDepartment of Chemistry, University of Oslo, P.O. Box 1033, Blindern, NO-0315 Oslo, Norway.ORCID 0000-0002-7871-3962
Elahe Jafari ChamgordaniDepartment of Chemistry, University of Oslo, P.O. Box 1033, Blindern, NO-0315 Oslo, Norway.
Britt PaulsenDepartment of Chemistry, University of Oslo, P.O. Box 1033, Blindern, NO-0315 Oslo, Norway.
Louis MaesUniversity of Antwerp, Laboratory of Microbiology, Parasitology and Hygiene, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Universiteitsplein 1, B-2610 Antwerp, Belgium.ORCID 0000-0002-2324-9509
An MatheeussenUniversity of Antwerp, Laboratory of Microbiology, Parasitology and Hygiene, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Lise-Lotte GundersenDepartment of Chemistry, University of Oslo, P.O. Box 1033, Blindern, NO-0315 Oslo, Norway.ORCID 0000-0002-4510-1118
Øyvind HalskauDepartment of Biological Sciences, University of Bergen, Thormøhlensgate 55, NO-5006 Bergen, Norway.ORCID 0000-0003-2517-1060
University of Oslo · NOUniversity of Antwerp · BEUniversity of Bergen · NONorwegian Geotechnical Institute · NO

Funding

Norges Forskningsråd 209330Norges Forskningsråd 240063
6 · The paper itself

Abstract

Marine sponges and soft corals have yielded novel compounds with antineoplastic and antimicrobial activities. Their mechanisms of action are poorly understood, and in most cases, little relevant experimental evidence is available on this topic. In the present study, we investigated whether agelasine D (compound

Indexed as

AlkaloidsAnimalsAnthozoaLipid BilayersMembrane LipidsPhosphatidylcholinesPhosphatidylethanolaminesPoriferaPurines1,2-oleoylphosphatidylcholine3,7-dihydro-3-methyl-7-((2E,6E,10Z)-3,7,11,15-tetramethyl-13-oxohexadeca-2,6,10-trien-1-yl)-6H-purin-6-oneagelasine DAlkaloidsdioleoyl phosphatidylethanolamineLipid BilayersMembrane LipidsPhosphatidylcholinesPhosphatidylethanolaminesPurines31P NMRagelasinelipidsmalonganenonemembrane affecting drug candidatesphase behavior

Identifiers

PMID32092956
PMCPMC7073740
OpenAlexW3009032383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.