ArticleInternational journal of molecular sciences2020
Integrated Metabolomic and Transcriptomic Analysis to Characterize Cutin Biosynthesis between Low- and High-Cutin Genotypes of
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Unravelling the genetics of heat-responsive fruit traits in pepper [Capsicum annuum L.] via GWAS under subtropical climates.BMC plant biology · 2026Article
- Uncovering the genetic architecture of pungency, carotenoids, and flavor inHorticulture research · 2025Article
- Recent Advances in Pepper Fruit Glossiness.Genes · 2025Review
- Exploring the sheen: a review of research advances on fruit glossiness.Frontiers in plant science · 2025Review
- Genetic tapestry of Capsicum fruit colors: a comparative analysis of four cultivated species.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Carotenoid retention during post-harvest storage of Capsicum annuum: the role of the fruit surface structure.Journal of experimental botany · 2024Article
- Fine mapping and candidate gene analysis of CaFCD1 affecting cuticle biosynthesis in Capsicum annuum L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Advances in Plant Metabolomics and Its Applications in Stress and Single-Cell Biology.International journal of molecular sciences · 2022Review
- Molecular Biology, Composition and Physiological Functions of Cuticle Lipids in Fleshy Fruits.Plants (Basel, Switzerland) · 2022Review
- Chile Pepper (Frontiers in plant science · 2022Review
- Precursor biosynthesis regulation of lignin, suberin and cutin.Protoplasma · 2021Review
- Review
- Mini Review: Transport of Hydrophobic Polymers Into the Plant Apoplast.Frontiers in plant science · 2020Review
- Metabolome and Transcriptome Profiling of Chicory Roots Provide Insights Into Laticifer Development and Specialized Metabolism.Physiologia plantarumArticle
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Habanero peppers constantly face biotic and abiotic stresses such as pathogen/pest infections, extreme temperature, drought and UV radiation. In addition, the fruit cutin lipid composition plays an important role in post-harvest water loss rates, which in turn causes shriveling and reduced fruit quality and storage. In this study, we integrated metabolome and transcriptome profiling pertaining to cutin in two habanero genotypes: PI 224448 and PI 257145. The fruits were selected by the waxy or glossy phenotype on their surfaces. Metabolomics analysis showed a significant variation in cutin composition, with about 6-fold higher cutin in PI 257145 than PI 224448. It also revealed that 10,16-dihydroxy hexadecanoic acid is the most abundant monomer in PI 257145. Transcriptomic analysis of high-cutin PI 257145 and low-cutin PI 224448 resulted in the identification of 2703 statistically significant differentially expressed genes, including 1693 genes upregulated and 1010 downregulated in high-cutin PI 257145. Genes and transcription factors such as GDSL lipase, glycerol-3 phosphate acyltransferase 6, long-chain acyltransferase 2, cytochrome P450 86A/77A, SHN1, ANL2 and HDG1 highly contributed to the high cutin content in PI 257145. We predicted a putative cutin biosynthetic pathway for habanero peppers based on deep transcriptome analysis. This is the first study of the transcriptome and metabolome pertaining to cutin in habanero peppers. These analyses improve our knowledge of the molecular mechanisms regulating the accumulation of cutin in habanero pepper fruits. These resources can be built on for developing cultivars with high cutin content that show resistance to biotic and abiotic stresses with superior postharvest appearance.
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