ArticleJournal of clinical gastroenterology
Deprescribing Proton Pump Inhibitors in an Academic, Primary Care Clinic: Quality Improvement Project.
Article in Journal of clinical gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06858384 (From Awareness to Action), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
From Awareness to Action: Transforming Proton Pump Inhibitor Use in Ras Al Khaimah Through Education and Intervention: the RAK -PRIDE Study
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Integrating patient education on deprescribing into care delivery: Learnings from the Optimize pragmatic trial.Patient education and counseling · 2026Trial
- The role of electronic health records systems in de-implementing low-value care in primary care: a scoping review.Implementation science communications · 2025Review
- Engaging Patients in Discussions About Medication Deprescribing.Journal of general internal medicine · 2025Article
- Potentially inappropriate medications for patients with heart failure: a nationwide retrospective study from 2012 to 2022.Journal of pharmaceutical policy and practice · 2025Article
- Approaches to Deprescribing Proton Pump Inhibitors in Clinical Practice: A Systematic Review.Journal of clinical medicine · 2024Review
- Impact of pharmacist-evaluated clinical decision support system alerts on potentially missing or inappropriately prescribed proton pump inhibitors at hospital discharge: a retrospective cross-sectional study.International journal of clinical pharmacy · 2024Article
- Determinants of and interventions for Proton Pump Inhibitor prescription behavior: A systematic scoping review.BMC primary care · 2024Article
- Advancing health equity in improving breast cancer screening with the use of a mobile mammography bus in marginalised population: quality improvement project.BMJ open quality · 2024Article
- Analysis of deprescription strategies of proton pump inhibitors in primary care: a narrative review.Primary health care research & development · 2023Review
- Effectiveness of a multi-faceted intervention to deprescribe proton pump inhibitors in primary care: protocol for a population-based, pragmatic, cluster-randomized controlled trial.BMC health services research · 2022Article
- Deprescribing Inappropriate Proton Pump Inhibitors in a Family Medicine Residency Practice Office.PRiMER (Leawood, Kan.) · 2021Article
- Patient Awareness of Reported Adverse Effects Associated with Proton Pump Inhibitors in a Medically Underserved Community.Healthcare (Basel, Switzerland) · 2020Article
- Appropriateness of proton pump inhibitor therapy in an ambulatory geriatrics clinic: A retrospective cross-sectional analysis.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPCArticle
- Observational
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
goalThe goal of this study was to reduce the percentage of inappropriately prescribed proton pump inhibitors (PPIs) in patients aged 50 and older from 80% (baseline) to 60% within 12 months in an academic, internal medicine clinic.
backgroundThe use of PPIs has increased drastically worldwide. Internal medicine clinic patients had inappropriate use of PPIs for an average of 4 to 5 years. STUDY: A multidisciplinary quality improvement team used the Plan-Do-Study-Act Model of health care improvement and performed a root cause analysis to identify barriers to inappropriate use of PPIs. The outcome measure was the percentage of patients inappropriately prescribed PPI. Process measures were completion rates of PPI risk assessment and esophagogastroduodenoscopy. Interventions included the creation of customized electronic health record templates and education to providers and patients. Analysis was performed using monthly statistical process control charts.
resultsThe average rate of PPI discontinuation was 51.1% (n=92/180), which corresponds to 30.0% inappropriate PPI usage within 12 months. The mean PPI discontinuation rate in the 1-year prestudy, study and 6 months poststudy period was 2.0%, 32.0%, and 49.7%, respectively. The mean esophagogastroduodenoscopy completion rate was 49.8% from the baseline of <30%.
conclusionsWe achieved a statistically significant and sustainable reduction of inappropriate PPI use to 30% from the baseline rates of 80% and surpassed our goal within 12 months. This quality improvement was unique as no pharmacy personnel was utilized in this process. The multifaceted strategies in a safety-net internal medicine clinic resulted in successful deprescribing of PPI and can be replicated in other setting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.