Evidence map›Paper›PMID 32091363›Full record

ArticleEmerging infectious diseases2020

Mycobacterium tuberculosis Beijing Lineage and Risk for Tuberculosis in Child Household Contacts, Peru.

Chuan-Chin Huang, Alexander L Chu, Mercedes C Becerra, Jerome T Galea, Roger Calderón, Carmen Contreras, Rosa Yataco, Zibiao Zhang, Leonid Lecca, Megan B Murray

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Active Case Finding for Tuberculosis in Migrants: a Systematic Review.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2024
    Pooled it
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  5. Molecular epidemiology ofJournal of clinical tuberculosis and other mycobacterial diseases · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chuan-Chin Huang
Alexander L Chu
Mercedes C Becerra
Jerome T Galea
Roger Calderón
Carmen Contreras
Rosa Yataco
Zibiao Zhang
Leonid Lecca
Megan B Murray
Brigham and Women's Hospital · USUniversity of South Florida · USHarvard University · USHarvard University Press · US

Funding

Metabolomics Core U19AI111224 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MURRAY, MEGAN, MURRAY, MEGAN B · 2015 to 2021
$20.4M
Real-time surveillance to support dynamic and predictive models of MDR/XDR TBU19AI076217 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MURRAY, MEGAN B · 2007 to 2011
$13.5M
NIAID NIH HHS U19 AI076217NIAID NIH HHS U19 AI111224
6 · The paper itself

Abstract

Few studies have prospectively compared the relative transmissibility and propensity to cause disease of Mycobacterium tuberculosis Beijing strains with other human-adapted strains of the M. tuberculosis complex. We assessed the effect of Beijing strains on the risk for M. tuberculosis infection and disease progression in 9,151 household contacts of 2,223 culture-positive pulmonary tuberculosis (TB) patients in Lima, Peru. Child contacts exposed to Beijing strains were more likely than child contacts exposed to non-Beijing strains to be infected at baseline, by 12 months of follow-up, and during follow-up. We noted an increased but nonsignificant tendency for child contacts to develop TB. Beijing strains were not associated with TB in adult contacts. These findings suggest that Beijing strains are more transmissible in children than are non-Beijing strains.

Indexed as

Family CharacteristicsAdolescentAdultAge FactorsChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMiddle AgedMycobacterium tuberculosisPeruProspective StudiesRisk FactorsbacteriaBCG vaccineinfection transmissionlatent tuberculosis infectionMycobacterium tuberculosisPeruTuberculosistuberculosis and other mycobacteria

Identifiers

PMID32091363
PMCPMC7045848
OpenAlexW3005743903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.