Evidence map›Paper›PMID 32090685›Full record

ArticleMolecular pain

Overexpression of microRNA-185 alleviates intervertebral disc degeneration through inactivation of the Wnt/

Zhennan Yun, Yuhang Wang, Wei Feng, Junting Zang, Daguang Zhang, Yuhang Gao

Abstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
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  15. Article
  16. Mechanobiology of MicroRNAs in Intervertebral Disk Degeneration.Journal of spine research and surgery · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhennan YunDepartment of Colorectal and Anal Surgery, The First Hospital of Jilin University, Changchun, P. R. China.
Yuhang WangDay Care Unit, The First Hospital of Jilin University, Changchun, P. R. China.
Wei FengDepartment of Orthopedics, The First Hospital of Jilin University, Changchun, P. R. China.
Junting ZangDepartment of Orthopedics, The First Hospital of Jilin University, Changchun, P. R. China.ORCID 0000-0003-3091-8229
Daguang ZhangDepartment of Orthopedics, The First Hospital of Jilin University, Changchun, P. R. China.
Yuhang GaoDepartment of Orthopedics, The First Hospital of Jilin University, Changchun, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Wnt Signaling PathwayAnimalsApoptosisAutophagybeta CateninCell SurvivalDown-RegulationGalectin 3Genes, ReporterIntervertebral DiscIntervertebral Disc DegenerationMaleMicroRNAsNucleus PulposusRatsRats, Sprague-Dawleybeta CateninGalectin 3Lgals3 protein, ratMicroRNAsMIRN185 microRNA, ratWnt ProteinsapoptosisautophagyGalectin-3intervertebral disc degenerationMicroRNA-185nucleus pulposus cellsWnt/β-catenin signaling pathway

Identifiers

PMID32090685
PMCPMC7040930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.