Evidence map›Paper›PMID 32090526›Full record

ArticleKorean journal of radiology2020

Thyroid-Associated Orbitopathy: Evaluating Microstructural Changes of Extraocular Muscles and Optic Nerves Using Readout-Segmented Echo-Planar Imaging-Based Diffusion Tensor Imaging.

Huan Huan Chen, Hao Hu, Wen Chen, Dai Cui, Xiao Quan Xu, Fei Yun Wu, Tao Yang

Abstract read
In one paragraph

Article in Korean journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Tractometry of Human Visual White Matter Pathways in Health and Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  16. Article
  17. Article
  18. Application of quantitative orbital analysis to assess the activity of Graves' ophthalmopathy.American journal of nuclear medicine and molecular imaging · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huan Huan Chen *Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0003-0201-2059
Hao Hu *Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-7983-7377
Wen ChenDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-4380-8013
Dai CuiDepartment of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0003-0356-3362
Xiao Quan XuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-5493-5256
Fei Yun WuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-3479-369X
Tao YangDepartment of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. njmu_yt@sina.com.ORCID 0000-0003-1883-4129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor imaging (DTI) in assessing the microstructural change of extraocular muscles (EOMs) and optic nerves in patients with thyroid-associated orbitopathy (TAO) as well as in evaluating disease activity. MATERIALS AND

methodsWe enrolled 35 TAO patients and 22 healthy controls (HCs) who underwent pre-treatment rs-EPI-based DTI. Mean, axial, and radial diffusivity (MD, AD, and RD) and fractional anisotropy (FA) of the medial and lateral EOMs and optic nerve for each orbit were calculated and compared between TAO and HC groups and between active and inactive TAO groups. Factors such as age, sex, disease duration, mediation, and smoking history between groups were also compared. Logistic regression analysis was used to evaluate the predictive value of significant variables for disease activity.

resultsDisease duration was significantly shorter in active TAOs than in inactive ones (

conclusionrs-EPI-based DTI is promising in assessing microstructural changes of EOMs and optic nerves and can help to indicate the disease activity of TAO, especially through the MD of medial EOMs.

Indexed as

AdultAgedArea Under CurveDiffusion Tensor ImagingEcho-Planar ImagingFemaleGraves OphthalmopathyHumansImage Processing, Computer-AssistedMaleMiddle AgedOculomotor MusclesOptic NerveROC CurveSensitivity and SpecificityThyroid GlandDiffusion tensor imagingExtraocular muscleOptic nerveReadout-segmented echo-planar imagingThyroid-associated orbitopathy

Identifiers

PMID32090526
PMCPMC7039723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.