Evidence map›Paper›PMID 32090502›Full record

Trial reportCancer medicine2020

Cost-effectiveness of the Collaborative Care to Preserve Performance in Cancer (COPE) trial tele-rehabilitation interventions for patients with advanced cancers.

Colleen F Longacre, John A Nyman, Sue L Visscher, Bijan J Borah, Andrea L Cheville

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Using digital technology to support wellbeing and independence among people living with incurable cancers: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Non-pharmacological interventions targeting mobility among people with advanced cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
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  8. Integrating Fitness Training in Oncologic Care: Lessons Learned from a Large Telemedicine Trial.Archives of rehabilitation research and clinical translation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Colleen F LongacreDivision of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, MN, USA.ORCID 0000-0002-5484-5004
John A NymanDivision of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, MN, USA.
Sue L VisscherCenter for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Bijan J BorahCenter for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Andrea L ChevilleDepartment of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-7668-6115

Funding

COllaborative Care to Preserve PErformance in Cancer (COPE) TrialR01CA163803 · NCI · MAYO CLINIC ROCHESTER · PI CHEVILLE, ANDREA LYNNE · 2012 to 2016
$3.1M
6 · The paper itself

Abstract

purposeThe purpose of this analysis was to determine the cost-effectiveness of a Collaborative Care Model (CCM)-based, centralized telecare approach to delivering rehabilitation services to late-stage cancer patients experiencing functional limitations.

methodsData for this analysis came from the Collaborative Care to Preserve Performance in Cancer (COPE) trial, a randomized control trial of 516 patients assigned to: (a) a control group (arm A), (b) tele-rehabilitation (arm B), and (c) tele-rehabilitation plus pharmacological pain management (arm C). Patient quality of life was measured using the EQ-5D-3L at baseline, 3-month, and 6-month follow-up. Direct intervention costs were measured from the experience of the trial. Participants' hospitalization data were obtained from their medical records, and costs associated with these encounters were estimated from unit cost data and hospital-associated utilization information found in the literature. A secondary analysis of total utilization costs was conducted for the subset of COPE trial patients for whom comprehensive cost capture was possible.

resultsIn the intervention-only model, tele-rehabilitation (arm B) was found to be the dominant strategy, with an incremental cost-effectiveness ratio (ICER) of $15 494/QALY. At the $100 000 willingness-to-pay threshold, this tele-rehabilitation was the cost-effective strategy in 95.4% of simulations. It was found to be cost saving compared to enhanced usual care once the downstream hospitalization costs were taken into account. In the total cost analysis, total inpatient hospitalization costs were significantly lower in both tele-rehabilitation (arm B) and tele-rehabilitation plus pain management (arm C) compared to control (arm A), (P = .048).

conclusionThe delivery of a CCM-based, centralized tele-rehabilitation intervention to patients with advanced stage cancer is highly cost-effective. Clinicians and care teams working with this vulnerable population should consider incorporating such interventions into their patient care plans.

Indexed as

Cost-Benefit AnalysisQuality of LifeAgedAntineoplastic Combined Chemotherapy ProtocolsCase-Control StudiesDecision Support TechniquesFemaleFollow-Up StudiesHumansMaleNeoplasmsPainPain ManagementPrognosisTelemedicineTelerehabilitationcost effectivnesshealthcare utilizationhospitalizationphysical functiontelecare

Identifiers

PMID32090502
PMCPMC7163089

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.