Evidence map›Paper›PMID 32090198›Full record

ArticleNature metabolism2020

Untargeted metabolomics links glutathione to bacterial cell cycle progression.

Johannes Hartl, Patrick Kiefer, Andreas Kaczmarczyk, Maximilian Mittelviefhaus, Fabian Meyer, Thomas Vonderach, Bodo Hattendorf, Urs Jenal, Julia A Vorholt

Open access · greenAbstract read
In one paragraph

Article in Nature metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Article
  3. The glutathione pathway is required for biofilm formation inCurrent research in microbial sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Regulation of potassium uptake inJournal of bacteriology · 2024
    Article
  14. Review
  15. Article
  16. Review
  17. Compound-Specific 1DACS omega · 2023
    Article
  18. Article
  19. Potential and Metabolic Pathways of Eugenol in the Management ofInternational journal of molecular sciences · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Johannes HartlETH Zurich, Institute of Microbiology, Zurich, Switzerland. hartlj@ethz.ch.ORCID http://orcid.org/0000-0001-8470-5355
Patrick Kiefer *ETH Zurich, Institute of Microbiology, Zurich, Switzerland.
Andreas Kaczmarczyk *Biozentrum of the University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-6616-1777
Maximilian MittelviefhausETH Zurich, Institute of Microbiology, Zurich, Switzerland.
Fabian MeyerETH Zurich, Institute of Microbiology, Zurich, Switzerland.
Thomas VonderachETH Zurich, Laboratory of Inorganic Chemistry, Zurich, Switzerland.
Bodo HattendorfETH Zurich, Laboratory of Inorganic Chemistry, Zurich, Switzerland.
Urs JenalBiozentrum of the University of Basel, Basel, Switzerland.
Julia A VorholtETH Zurich, Institute of Microbiology, Zurich, Switzerland. jvorholt@ethz.ch.ORCID http://orcid.org/0000-0002-6011-4910
ETH Zurich · CHUniversity of Basel · CH

Funding

Swiss National Science Foundation 147090Swiss National Science Foundation 173094
6 · The paper itself

Abstract

Cell cycle progression requires the coordination of cell growth, chromosome replication, and division. Consequently, a functional cell cycle must be coupled with metabolism. However, direct measurements of metabolome dynamics remained scarce, in particular in bacteria. Here, we describe an untargeted metabolomics approach with synchronized

Indexed as

Cell CycleMetabolomicsCaulobacter crescentusCell DivisionChromatography, LiquidGlutathioneHomeostasisMass SpectrometryPotassiumGlutathionePotassium

Identifiers

PMID32090198
PMCPMC7035108
OpenAlexW3003204739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.