Evidence map›Paper›PMID 32090158›Full record

ArticleData in brief2020

Correlative Brillouin and Raman spectroscopy data acquired on single cells.

Silvia Caponi, Sara Mattana, Maurizio Mattarelli, Martina Alunni Cardinali, Lorena Urbanelli, Krizia Sagini, Carla Emiliani, Daniele Fioretto

Abstract read
In one paragraph

Article in Data in brief, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia CaponiIstituto Officina dei Materiali del CNR (CNR-IOM)-Unità di Perugia, University of Perugia, Perugia, I-06123, Italy.
Sara MattanaDepartment of Physics, University of Florence, Via G. Sansone 1, 50019, Sesto Fiorentino, Italy.
Maurizio MattarelliDepartment of Physics and Geology, University of Perugia, Perugia, I-06123, Italy.
Martina Alunni CardinaliDepartment of Physics and Geology, University of Perugia, Perugia, I-06123, Italy.
Lorena UrbanelliDepartment of Chemistry, Laboratory of Biochemistry and Molecular Biology, Biology and Biotechnology, University of Perugia, Via del Giochetto, Perugia, I-06123, Italy.
Krizia SaginiDepartment of Chemistry, Laboratory of Biochemistry and Molecular Biology, Biology and Biotechnology, University of Perugia, Via del Giochetto, Perugia, I-06123, Italy.
Carla EmilianiDepartment of Chemistry, Laboratory of Biochemistry and Molecular Biology, Biology and Biotechnology, University of Perugia, Via del Giochetto, Perugia, I-06123, Italy.
Daniele FiorettoDepartment of Physics and Geology, University of Perugia, Perugia, I-06123, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distribution of chemical species and the mechanical modulation inside a single cell or tissue are of fundamental importance to characterize their physiological activity or their pathological conditions [1-4]. Here we analyse these properties by means of label free, non invasive, spectroscopic methods. In particular, we use a recently developed micro-spectrometer, which acquires simultaneously Raman and Brillouin spectra on the same point with subcellular resolution [5]. The techniques ability to analyse the chemical composition and the mechanical properties of single cells has been tested on NIH/3T3 murine fibroblast cells grown in adhesion on silicon substrates. Here we report the data acquired from fixed cells after their oncogenic transformation. Mechanical and chemical evolution is evident by direct inspection of raw data. Sharing our experimental records can be valuable for researchers interested in the analysis of single cells by Raman and Brillouin spectroscopy in order: i) to compare data acquired by different set-ups and ii) to correctly model the fitting functions.

Indexed as

BiophotonicsBrillouin spectroscopyCell mechanicsRaman spectroscopy

Identifiers

PMID32090158
PMCPMC7026319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.