Evidence map›Paper›PMID 32089981›Full record

Article3 Biotech2020

Expression and immunoreactivity of a recombinant multi-epitope antigen designed based on four major structural proteins of avian infectious bronchitis virus.

Qing Liu, Jin Li, Run-Li Li, Ye-Ting Ma, Peng-Lai Zhou, Wen-Wei Gao, Hai-Li Ma

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qing Liu *College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801 Shanxi People's Republic of China.
Jin Li *College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801 Shanxi People's Republic of China.
Run-Li LiCollege of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801 Shanxi People's Republic of China.
Ye-Ting MaCollege of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801 Shanxi People's Republic of China.
Peng-Lai ZhouCollege of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801 Shanxi People's Republic of China.
Wen-Wei GaoCollege of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801 Shanxi People's Republic of China.ORCID 0000-0002-7878-5237
Hai-Li MaCollege of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801 Shanxi People's Republic of China.
Shanxi Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of rapid, simple, and sensitive diagnostic methods for identification of avian infectious bronchitis virus (IBV) is crucial for the effective control of avian infectious bronchitis. In the present study, a tandemly arranged multiepitope peptide (named SEMN) was designed with four antigenic regions derived from four major structural proteins of IBV. Then, we performed codon optimization of SEMN gene by changing the codon-adaptation index from 0.45 to 0.94 and expressed the optimized gene in codon bias-adjusted

Indexed as

Avian infectious bronchitis virusImmunoreactivityMulti-epitope antigenProkaryotic expression

Identifiers

PMID32089981
PMCPMC7000575
OpenAlexW3003753626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.