ArticleSleep disorders2020
Daytime QT by Routine 12-Lead ECG Is Prolonged in Patients with Severe Obstructive Sleep Apnea.
Article in Sleep disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Evaluation of quality of life after orthognathic surgery in obstructive sleep apnea syndrome: a systematic review.The Angle orthodontist · 2025Pooled it
- Sleep Apnea: The Slept-Upon Cardiovascular Risk Factor.Biomedicines · 2025Review
- Association of electrocardiogram features with risk of obstructed sleep apnea: a population-based cohort study.Sleep & breathing = Schlaf & Atmung · 2025Article
- A QTc risk score in patients with obstructive sleep apnea.Sleep medicine · 2023Article
- QTPhysiological reports · 2022Article
- Markers of ventricular repolarization and overall mortality in sleep disordered breathing.Sleep medicine · 2022Article
- QTc prolongation is associated with severe desaturations in stroke patients with sleep apnea.BMC pulmonary medicine · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundObstructive sleep apnea (OSA) has been linked to sudden cardiac death (SCD). Prolonged QT is a recognized electrocardiographic (ECG) marker of abnormal ventricular repolarization linked to increased risk of SCD. We hypothesized that individuals with OSA have more pronounced abnormality in daytime QT interval.
methodsWe reviewed consecutive patients who underwent clinically indicated polysomnography with 12-lead ECG within 1 year at a single center. Heart rate-corrected QT interval (QTc) was compared by OSA severity class (normal/mild: apnea-hypopnea index (AHI) < 15/hr (
resultsA total of 249 patients were included. QTc was similar between the normal/mild and moderate groups, and the overall QTc trend increased across OSA (normal/mild: 435.6 ms; moderate: 431.36; severe: 444.4;
conclusionsIn a sleep clinic cohort, severe OSA was associated with higher QTc and clinically defined abnormal QTc compared with nonsevere OSA.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.