Evidence map›Paper›PMID 32089817›Full record

ArticleParkinson's disease2020

Phosphorylated Alpha-Synuclein in Red Blood Cells as a Potential Diagnostic Biomarker for Multiple System Atrophy: A Pilot Study.

Xu-Ying Li, Weiwei Yang, Xin Li, Xu-Ran Li, Wei Li, Qihan Song, Linjuan Sun, Feng Lin, Zhigang Chen, Chaodong Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Parkinson's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Fluid biomarkers in atypical Parkinsonism: current state and future perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  4. Article
  5. Posttranslational Modifications ofPharmacological reviews · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Synuclein in red blood cells: a potential biomarker for multiple system atrophy, and other updates on recent autonomic research.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Xu-Ying LiDepartment of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.ORCID https://orcid.org/0000-0001-6995-8258
Weiwei YangDepartment of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.ORCID https://orcid.org/0000-0001-7270-9199
Xin LiDepartment of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.ORCID https://orcid.org/0000-0002-9637-6090
Xu-Ran LiDepartment of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Wei LiDepartment of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Qihan SongDepartment of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.ORCID https://orcid.org/0000-0003-0610-8752
Linjuan SunDepartment of Neurology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.ORCID https://orcid.org/0000-0001-6710-3395
Feng LinDepartment of Neurology, Union Hospital of Fujian Medical University, Fuzhou 350001, China.ORCID https://orcid.org/0000-0001-5536-0634
Zhigang ChenDepartment of Neurology, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China.ORCID https://orcid.org/0000-0002-9675-5920
Chaodong WangDepartment of Neurology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.ORCID https://orcid.org/0000-0001-8784-1002
Shun YuDepartment of Neurobiology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.ORCID https://orcid.org/0000-0002-2591-9764
Capital Medical University · CNBeijing University of Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNFujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of multiple system atrophy (MSA) remains a challenge, due to the complexity and overlapping of its symptoms with other Parkinsonian disorders. The critical role of alpha-synuclein (

Identifiers

PMID32089817
PMCPMC7013322
OpenAlexW3003798971

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.