Evidence map›Paper›PMID 32089720›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Usefulness of a Kampo Medicine on Stress-Induced Delayed Gastric Emptying in Mice.

Sachiko Mogami, Ryutaro Arita, Miwa Nahata, Naoki Fujitsuka, Shin Takayama, Tadashi Ishii

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Biochemistry and biophysics reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sachiko MogamiTsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan.ORCID https://orcid.org/0000-0001-7914-4928
Ryutaro AritaDepartment of Education and Support for Regional Medicine, Department of Kampo Medicine, Tohoku University Hospital, Sendai, Miyagi 980-8574, Japan.
Miwa NahataTsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan.ORCID https://orcid.org/0000-0002-4462-6887
Naoki FujitsukaTsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan.ORCID https://orcid.org/0000-0003-0856-5850
Shin TakayamaDepartment of Education and Support for Regional Medicine, Department of Kampo Medicine, Tohoku University Hospital, Sendai, Miyagi 980-8574, Japan.ORCID https://orcid.org/0000-0002-6388-4566
Tadashi IshiiDepartment of Education and Support for Regional Medicine, Department of Kampo Medicine, Tohoku University Hospital, Sendai, Miyagi 980-8574, Japan.
Tsumura Research Institute (Japan) · JPTohoku University · JPTohoku University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety and depression often occur with gastrointestinal symptoms. Although the Japanese traditional medicine (Kampo medicine) bukuryoingohangekobokuto (BGH) is approved for treating anxiety, neurotic gastritis, and heartburn, its effect on gastrointestinal motility remains poorly known. This study aimed to examine the effect of BGH on delayed gastric emptying in stress model mice and clarified its action mechanism. Seven-week-old C57BL/6 male mice were acclimated for a week and fasted overnight. Stress hormone, corticotropin-releasing factor (CRF), was intracerebroventricularly injected to mice, and solid nutrient meal (ground chow and distilled water) was orally administered 1 hour after. Gastric contents were collected to evaluate gastric emptying rates by measuring its dry weight. Injection of CRF (0.3 or 1.0

Identifiers

PMID32089720
PMCPMC7013301
OpenAlexW3003341779

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.