Evidence map›Paper›PMID 32089643›Full record

ArticleMediators of inflammation2020

Regulation of Cyclooxygenase 2 by

Marjan Nokhbehsaim, Andressa V B Nogueira, Sandor Nietzsche, Sigrun Eick, James Deschner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Journal of dental research · 2021
    Article
  6. International journal of molecular sciences · 2021
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Marjan NokhbehsaimSection of Experimental Dento-Maxillo-Facial Medicine, Center of Dento-Maxillo-Facial Medicine, University of Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0003-0998-1717
Andressa V B NogueiraDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.ORCID https://orcid.org/0000-0002-2756-5947
Sandor NietzscheCenter of Electron Microscopy, University Hospital Jena, Jena, Germany.
Sigrun EickDepartment of Periodontology, Laboratory of Oral Microbiology, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-4619-2461
James DeschnerDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.ORCID https://orcid.org/0000-0002-8808-8769
Johannes Gutenberg University Mainz · DEJena University Hospital · DEUniversity of Bern · CHUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is a prevalent chronic inflammatory disease triggered by a synergistic and dysbiotic microbiota present in the oral biofilm. This in vitro study is aimed at evaluating the regulation of cyclooxygenase (COX)2 expression and production by the periodontopathogen

Indexed as

Cell LineCyclooxygenase 2Enzyme-Linked Immunosorbent AssayEubacterialesFibroblastsHumansMicroscopy, Electron, ScanningMonocytesPolymerase Chain ReactionReal-Time Polymerase Chain ReactionTHP-1 CellsTumor Necrosis Factor-alphaCyclooxygenase 2Tumor Necrosis Factor-alpha

Identifiers

PMID32089643
PMCPMC7023199
OpenAlexW3005311652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.