ArticleWorld journal of gastroenterology2020
Development of a prognostic model for one-year surgery risk in Crohn's disease patients: A retrospective study.
Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Totally stapled Kono-S anastomosis for Crohn's disease.Techniques in coloproctology · 2022Trial
- Integrating inflammatory and coagulation biomarkers for surgical risk stratification and treatment benefit assessment in Crohn's disease.Frontiers in immunology · 2026Article
- A modified totally stapled KONO-S anastomosis for ileal and ileo-colic Crohn's disease: technical aspects and case series.Updates in surgery · 2025Article
- Kono-S anastomosis in Crohn's disease: initial experience in pediatric patients.Pediatric surgery international · 2024Article
- Mathematical Models Including microRNA Levels of Mesenteric Adipose Tissue May Predict Postoperative Relapse in Crohn's Disease Patients.Gastro hep advances · 2024Article
- A Logistic Regression Model for Predicting the Risk of Subsequent Surgery among Patients with Newly Diagnosed Crohn's Disease Using a Brute Force Method.Diagnostics (Basel, Switzerland) · 2023Article
- Methotrexate showed efficacy both in Crohn's disease and ulcerative colitis, predictors of surgery were identified in patients initially treated with methotrexate monotherapy.Frontiers in pharmacology · 2022Article
- Development of a Clinical and Genetic Prediction Model for Early Intestinal Resection in Patients with Crohn's Disease: Results from the IMPACT Study.Journal of clinical medicine · 2021Article
- [Drug treatment of chronic inflammatory bowel diseases-What must the surgeon know and perioperatively pay attention to?]Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Prophylaxis of Crohn's disease recurrence: A surgeon's perspective.Annals of gastroenterological surgery · 2020Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccelerated therapeutic treatment should be considered in patients with progressive Crohn's disease (CD) to prevent complications as well as surgery. Therefore, screening for risk factors and predicting the need for early surgery are of great importance in clinical practice.
aimTo establish a model to predict CD-related early surgery.
methodsThis was a retrospective study collecting data from CD patients diagnosed at our inflammatory bowel disease center from January 1, 2012 to December 31, 2016. All data were randomly stratified into a training set and a testing set at a ratio of 8:2. Multivariable logistic regression analysis was conducted with receiver operating characteristic curves constructed and areas under the curve calculated. This model was further validated with calibration and discrimination estimated. A nomogram was finally developed.
resultsA total of 1002 eligible patients were enrolled with a mean follow-up period of 53.54 ± 13.10 mo. In total, 24.25% of patients received intestinal surgery within 1 year after diagnosis due to complications or disease relapse. Disease behavior (B2: OR [odds ratio] = 6.693,
conclusionThis prognostic model can effectively predict 1-year risk of CD-related intestinal surgery, which will assist in screening progressive CD patients and tailoring therapeutic management.
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