Evidence map›Paper›PMID 32089572›Full record

ReviewIndian journal of microbiology2020

Reconciling Hygiene and Cleanliness: A New Perspective from Human Microbiome.

Vipin Gupta, Roshan Kumar, Utkarsh Sood, Nirjara Singhvi

Abstract readReview
In one paragraph

Review in Indian journal of microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The impact ofFrontiers in cellular and infection microbiology · 2025
    Pooled it
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Weaponising microbes for peace.Microbial biotechnology · 2023
    Article
  9. Conversations in the Gut: The Role of Quorum Sensing in Normobiosis.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Diet, Gut Microbiota and COVID-19.Indian journal of microbiology · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vipin Gupta *PhiXGen Private Limited, Gurugram, Haryana 122001 India.ORCID 0000-0002-6819-7087
Roshan Kumar *2P.G. Department of Zoology, Magadh University, Bodh-Gaya, Bihar 824231 India.
Utkarsh Sood *3The Energy and Resources Institute, Darbari Seth Block, IHC Complex, Lodhi Road, New Delhi, 110003 India.
Nirjara Singhvi4Department of Zoology, University of Delhi, Delhi, Delhi 110007 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term hygiene is deeply rooted with the concept of maintaining sound health and alertness towards cleanliness, while "hygiene hypothesis" depicts the protective role of microbial community exposure in development of early immunity and initial allergic and aesthetic reactions. The tug-of-war has now been pushed toward the literal term "hygiene" over the "hygiene hypothesis" and has continued with disinfection of all microbial loads from the related environments to avoid infections in humans. With the advancement in the microbiome studies, it became clear that humans possess warm, and significant relationships with diverse microbial community. With this opinion article, we have emphasized on the importance of hygiene hypothesis in immunological responses. We also propose the individual/targeted hygiene instead of application of unanimous hygiene hypothesis. This review also elaborates the common practices that should be employed to maintain hygiene along with the balanced microbiome.

Indexed as

AllergiesHygieneOld friend hypothesisTargeted hygiene

Identifiers

PMID32089572
PMCPMC7000587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.