ReviewFertility and sterility2020
Harnessing the full potential of reproductive genetics and epigenetics for male infertility in the era of "big data".
Review in Fertility and sterility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Artificial Intelligence-Driven Reproductive Bioengineering: Integrating Fertility Diagnostics, Organ-on-Chip Systems, Cryobiology and Epigenetic Safety for Precision Reproductive Medicine.Bioengineering (Basel, Switzerland) · 2026Review
- Mendelian randomization in ovarian research: applications in PCOS, ovarian aging, and assisted reproductive technology.Journal of ovarian research · 2026Review
- Article
- Empirical Treatments for Male Infertility: A Focus on Lifestyle Modifications and Medicines.Diseases (Basel, Switzerland) · 2024Review
- Molecular Markers: A New Paradigm in the Prediction of Sperm Freezability.International journal of molecular sciences · 2023Review
- Epigenetics Role in Spermatozoa Function: Implications in Health and Evolution-An Overview.Life (Basel, Switzerland) · 2023Review
- The Role ofJournal of clinical medicine · 2023Article
- Infertility in Men: Advances towards a Comprehensive and Integrative Strategy for Precision Theranostics.Cells · 2022Review
- Can fever alone alter sperm parameters after severe acute respiratory syndrome coronavirus 2 infection?Fertility and sterility · 2022Article
- Epigenetic Modifications, A New Approach to Male Infertility Etiology: A Review.International journal of fertility & sterility · 2022Review
- Metabolic syndrome and male fertility disorders: Is there a causal link?Reviews in endocrine & metabolic disorders · 2021Review
- Testicular Stem Cell Dysfunction Due to Environmental Insults Could Be Responsible for Deteriorating Reproductive Health of Men.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Epigenetics of Male Infertility: The Role of DNA Methylation.Frontiers in cell and developmental biology · 2021Review
- Web- and Artificial Intelligence-Based Image Recognition For Sperm Motility Analysis: Verification Study.JMIR medical informatics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The complexity of male reproductive impairment has hampered characterization of the underlying genetic causes of male infertility. However, in the last 20 years, more powerful and affordable tools to interrogate the genetic and epigenetic determinants of male infertility have accelerated the number of new discoveries in the characterization of male infertility. With this explosion of new data, integration in a systems-based approach-including complete phenotypic information-to male infertility is imperative. We briefly review the current understanding of genetic and epigenetic causes of male infertility and how findings may be translated into a practical component for the diagnosis and treatment of male infertility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.