Evidence map›Paper›PMID 32089145›Full record

ArticleEpidemiology and infection2020

High number of hospitalisations and non-classical presentations: lessons learned from a measles outbreak in 2017, Belgium.

L Cornelissen, T Grammens, S Leenen, C Schirvel, V Hutse, R Demeester, B Swennen, T Asikainen, C Wyndham-Thomas

Open access · goldAbstract read
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Article in Epidemiology and infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

L CornelissenService of Epidemiology of Infectious Diseases, Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.ORCID 0000-0002-4550-9439
T GrammensService of Epidemiology of Infectious Diseases, Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
S LeenenInfectious Disease Surveillance Unit, Agence pour une Vie de Qualité (AVIQ), Walloon region, Charleroi, Belgium.
C SchirvelInfectious Disease Surveillance Unit, Agence pour une Vie de Qualité (AVIQ), Walloon region, Charleroi, Belgium.
V HutseNational Reference Centre for Measles, Mumps and Rubella, Service of Viral Diseases, Sciensano, Brussels, Belgium.
R DemeesterCentre Hospitalier Universitaire de Charleroi, Charleroi, Belgium.
B SwennenPublic Health School - Université Libre de Bruxelles, Brussels, Belgium.
T AsikainenService of Epidemiology of Infectious Diseases, Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
C Wyndham-ThomasService of Epidemiology of Infectious Diseases, Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Sciensano (Belgium) · BEGrand Charleroi Hospital · BEUniversité Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe and analyse an outbreak of measles that affected Belgium early 2017. In total, 289 cases were reported, mostly (53%) in people 15 years or older. For 133 (46%) vaccination status was unknown and a further 117 (41%) were not vaccinated. According to national guidelines, 83 of the unvaccinated cases (29% of total cases) should have received minimum one dose of vaccine, but did not. One in five cases (21%) did not present with the classical triad of fever, rash and any of coryza, conjunctivitis or cough. Rash was the most sensitive symptom, being absent in only six cases. A large proportion of cases (125/289, 43%) required hospitalisation. In hospitalised patients, the most commonly observed complications were hepatic disorders (present in 58/125 hospitalised patients, 46%). Thirty-six of the cases (12%) were in healthcare workers and nosocomial spread contributed importantly to the outbreak. Older age at presentation, altered clinical presentations and presence of complications like hepatitis can delay the correct diagnosis of measles. Clinicians should maintain a high index of suspicion in any individual presenting with rash. If the elimination target is to be reached, catch-up vaccination campaigns should be intensified and target young adults and health care workers.

Indexed as

Disease OutbreaksAdolescentAdultAgedAged, 80 and overBelgiumChildChild, PreschoolCross InfectionDisease Transmission, InfectiousFemaleHospitalizationHumansInfantInfant, NewbornMaleEpidemiologymeasles (rubeola)notifiable infectious diseasesoccupation-related infectionsvaccine preventable diseases

Identifiers

PMID32089145
PMCPMC7058656
OpenAlexW3007186898

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.