ArticleJournal of the American Heart Association2020
Endovascular Treatment of Very Elderly Patients Aged ≥90 With Acute Ischemic Stroke.
Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Mechanical Thrombectomy in Nonagenarians: a Systematic Review and Meta-analysis.Translational stroke research · 2021Pooled it
- Evaluating the impact of frailty in older adults on functional outcomes post-mechanical thrombectomy: a multicentre study incorporating traditional and machine learning methods.Journal of thrombosis and thrombolysis · 2026Article
- Impact of age on clinical outcomes after endovascular therapy for large ischemic stroke.Journal of neurology · 2026Article
- Early surrogates of functional outcome after thrombectomy for MCA-M2 occlusions.Scientific reports · 2026Article
- Safety of endovascular therapy in ischemic stroke patients ⩾90 years: A cohort study from the EVA-TRISP collaboration.European stroke journal · 2026Observational
- Anesthesia Considerations in Older Adults Undergoing Emergency Mechanical Thrombectomy for Acute Ischaemic Stroke.Drugs & aging · 2025Review
- Safety of endovascular therapy in ischemic stroke patients ⩾90 years: A cohort study from the EVA-TRISP collaboration.European stroke journal · 2025Article
- Outcomes of different anesthesia techniques in nonagenarians treated with mechanical thrombectomy for anterior circulation large vessel occlusion: An inverse probability weighting analysis.European stroke journal · 2025Article
- Systemic Comorbidities as Modifiers of Outcome After Endovascular Thrombectomy for Acute Ischemic Stroke.Current neurology and neuroscience reports · 2025Review
- Mechanical thrombectomy in stroke patients of advanced age with score-based prediction of outcome.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Safety and efficacy of bridging intravenous thrombolysis plus mechanical thrombectomy versus direct mechanical thrombectomy in different age groups of acute ischemic stroke patients.Acta neurologica Belgica · 2025Article
- Acute stroke in persons 85 years or older-clinical characteristics, impact of frailty, and predictors of outcome.Frontiers in neurology · 2025Article
- Brain Frailty on Neuroimaging Beyond Chronological Age Is Associated with Functional Outcome After Endovascular Thrombectomy in Patients with Anterior Large Vessel Occlusion.Therapeutics and clinical risk management · 2025Article
- Prognostic value of temporalis muscle thickness as a marker of sarcopenia in intracerebral hemorrhage.Frontiers in neurology · 2025Article
- Temporalis muscle thickness as a predictor of functional outcome after reperfusion therapies for acute ischemic stroke: a retrospective, cohort study.Journal of neurology · 2024Article
- Stress hyperglycemia is associated with futile recanalization in patients with anterior large vessel occlusion undergoing mechanical thrombectomy.European stroke journal · 2024Article
- Predictors of favorable functional outcomes for elderly patients undergoing endovascular thrombectomy for acute ischemic stroke.European journal of medical research · 2024Observational
- Predictors of futile recanalization in nonagenarians treated with mechanical thrombectomy: a multi-center observational study.Journal of neurology · 2024Observational
- Endovascular thrombectomy for acute ischemic stroke in elderly patients with large ischemic cores.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients.Geriatrics (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
19 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Patients aged ≥90 were excluded or under-represented in past thrombectomy trials; thus, uncertainty remains whether treatment benefits can be expected regardless of age. This study investigates outcome and safety of thrombectomy in nonagenarians to improve decision making in a real-world setting. Methods and Results All currently available data of patients aged ≥90 enrolled in the GSR-ET (German Stroke Registry-Endovascular Treatment) were combined with a smaller cohort from 3 tertiary stroke centers. Baseline characteristics, procedural (Thrombolysis in Cerebral Infarction scale) and functional outcomes (modified Rankin Scale; mRS), as well as complications (symptomatic intracranial hemorrhage, serious adverse events; SAEs) were analyzed. Good functional outcome was defined as mRS ≤3 at 90-days. 203 patients with anterior circulation stroke and prestroke mRS ≤3 were included. The rate of successful recanalization (Thrombolysis in Cerebral Infarction scale ≥2b) was 75.9% (154/203). Good functional outcome (mRS ≤3) was observed in 21.6% (41 of 193) at 90-days. In-hospital mortality was 27.1% (55 of 203) and increased significantly at 90 days to 48.9% (93 of 190;
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.