Evidence map›Paper›PMID 32088972›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias

Nutritional and Functional Indicators and Their Association With Mortality Among Older Adults With Alzheimer's Disease.

O Vicente de Sousa, J Mendes, T F Amaral

Abstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  6. Review
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  13. The Impact of Diet Type on Weight Loss in Patients with Alzheimer's Disease.American journal of Alzheimer's disease and other dementias
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

O Vicente de SousaPsychogeriatrics Unit of Hospital de Magalhães Lemos E.P.E., Porto, Portugal.ORCID 0000-0001-9878-5990
J MendesFaculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal.
T F AmaralFaculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal.ORCID 0000-0002-3998-6730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated how different nutritional and functional status indicators are associated with mortality in patients with Alzheimer's disease (AD). A prospective cohort study was conducted among 79 community-dwelling older adults with AD. Follow-up was 60 months. Undernutrition status was evaluated by Mini Nutritional Assessment (MNA), body mass index, mid-arm muscle circumference (MAMC), calf circumference, and phase angle. Functional status was assessed by handgrip strength, and usual gait speed. Twenty-two participants died (27.8%). Results show that undernutrition (hazard ratio [HR] 5.69, 95% confidence interval [CI] 2.21-14.61), weight loss (HR 3.82, 95% CI 1.37-10.63), underweight (HR 3.24, 95% CI 1.18-8.82), low MAMC (HR 4.54, 95% CI 1.65-12.48), calf circumference ≤ 31 (HR 4.27, 95% CI 1.63-11.16), low HGS (HR 3.11, 95% CI 1.18-8.17), and low gait speed (HR 4.73, 95% CI 1.68-13.27) were all associated with mortality. In conclusion, a poor nutritional and functional status was associated with a higher risk of mortality, regardless of sex, age, marital status, education, and cognitive function.

Indexed as

Nutritional StatusNutrition AssessmentPhysical Functional PerformanceAgedAged, 80 and overAlzheimer DiseaseBody Mass IndexFemaleHand StrengthHumansIndependent LivingMaleMiddle AgedProspective StudiesAlzheimer’s diseasecommunity-dwellingfunctional performancemortalitynutritional status

Identifiers

PMID32088972
PMCPMC10624010

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.