Evidence map›Paper›PMID 32088851›Full record

ArticleJournal of fluorescence2020

Design and Synthesis of New Porphyrin Analogues as Potent Photosensitizers for Photodynamic Therapy: Spectroscopic Approach.

Prasad G Mahajan, Nilam C Dige, Balasaheb D Vanjare, Chong-Hyeak Kim, Sung-Yum Seo, Ki Hwan Lee

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Investigation of singlet oxygen quantum yield of protonated water-soluble glycosylated porphyrin photosensitizer for photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. ACS medicinal chemistry letters · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Prasad G MahajanDepartment of Chemistry, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea.
Nilam C DigeDepartment of Biological Sciences, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea.
Balasaheb D VanjareDepartment of Chemistry, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea.
Chong-Hyeak KimCenter for Chemical Analysis, Korea Research Institute of Chemical Technology, Yuseong, Daejeon, 34114, Republic of Korea.
Sung-Yum SeoDepartment of Biological Sciences, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea.
Ki Hwan LeeDepartment of Chemistry, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea. khlee@kongju.ac.kr.ORCID http://orcid.org/0000-0002-5553-4849
Kongju National University · KRKorea Research Institute of Chemical Technology · KR

Funding

National Research Foundation of Korea NRF- 2019R1I1A3A01059089
6 · The paper itself

Abstract

New porphyrin analogues have been designed and synthesized using pyrrole, various aldehydes and propionic acid. The formation of desired compounds was analyzed by utilizing the spectral analysis such as IR, NMR and Mass spectroscopy. The studies on absorption and fluorescence emission of synthesized porphyrins were used to evaluate photophysical characteristics such as molar excitation coefficient and Stokes shift. The estimated values of fluorescence lifetime and fluorescence quantum yield of synthesized porphyrins were found to be variable due to the presence of change in the electron donating and withdrawing characters. The efficiency of generation of singlet oxygen by each synthesized porphyrin as photosensitizer was measured in terms of singlet oxygen quantum yield through photooxidation of 9,10-dimethylantharacene. The obtained singlet oxygen quantum yield values were found to be higher in case of porphyrins those have more electron withdrawing characters rather than donating characters as compared to reference 5,10,15,20-tetraphenylporphyrin (H

Indexed as

Drug DesignPhotochemotherapyMolecular StructurePhotosensitizing AgentsPorphyrinsSpectrometry, FluorescencePhotosensitizing AgentsPorphyrinsPhotodynamic therapyPhotophysical propertiesPhotosensitizersPorphyrin analoguesSinglet oxygen

Identifiers

PMID32088851
OpenAlexW3006777955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.