Evidence map›Paper›PMID 32088833›Full record

ReviewMolecular and cellular biochemistry2020

Inside(sight) of tiny communicator: exosome biogenesis, secretion, and uptake.

Anshul S Jadli, Noura Ballasy, Pariya Edalat, Vaibhav B Patel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 211 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Dengue virus harnesses mosquito Syntenin to load and secrete viral RNA into salivary exosomes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Exosomes promise better bone regeneration.Regenerative therapy · 2025
    Review
  13. Review
  14. Review
  15. Exosome: an overview on enhanced biogenesis by small molecules.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  16. Review
  17. Extracellular Vesicles and Immune Activation in Solid Organ Transplantation: The Impact of Immunosuppression.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  18. Current Understanding of the Exosomes and Their Associated Biomolecules in the Glioblastoma Biology, Clinical Treatment, and Diagnosis.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Review
  19. Review
  20. Review

83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anshul S JadliDepartment of Physiology and Pharmacology, Cumming School of Medicine, The University of Calgary, HMRB-53, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.
Noura BallasyDepartment of Physiology and Pharmacology, Cumming School of Medicine, The University of Calgary, HMRB-53, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.
Pariya EdalatDepartment of Physiology and Pharmacology, Cumming School of Medicine, The University of Calgary, HMRB-53, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.
Vaibhav B PatelDepartment of Physiology and Pharmacology, Cumming School of Medicine, The University of Calgary, HMRB-53, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada. vaibhav@ucalgary.ca.ORCID http://orcid.org/0000-0001-5917-5962
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discovered in the late 1980s as an extracellular vesicle of endosomal origin secreted from reticulocytes, exosomes recently gained scientific attention due to its role in intercellular communication. Exosomes have now been identified to carry cell-specific cargo of nucleic acids, proteins, lipids, and other biologically active molecules. Exosomes can be selectively taken up by neighboring or distant cells, which has shown to result in structural and functional responses in the recipient cells. Recent advances indicate the regulation of exosomes at various steps, including their biogenesis, selection of their cargo, as well as cell-specific uptake. This review will shed light on the differences between the type of extracellular vesicles. In this review, we discuss the recent progress in our understanding of the regulation of exosome biogenesis, secretion, and uptake.

Indexed as

Biological TransportCell CommunicationExosomesHumansReticulocytesBiogenesisExosomesExtracellular vesiclesIntercellular communicationSecretion

Identifiers

PMID32088833
OpenAlexW3007279081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.