Evidence map›Paper›PMID 32088788›Full record

ArticleMikrochimica acta2020

Immunomagnetic bead-based bioassay for the voltammetric analysis of the breast cancer biomarker HER2-ECD and tumour cells using quantum dots as detection labels.

Maria Freitas, Henri P A Nouws, Elisa Keating, Virginia Cruz Fernandes, Cristina Delerue-Matos

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  6. FeBiosensors · 2023
    Article
  7. Review
  8. Article
  9. Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria FreitasREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Politécnico do Porto, R. Dr. António Bernardino de Almeida 431, 4200-072, Porto, Portugal.ORCID https://orcid.org/0000-0002-0628-2753
Henri P A NouwsREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Politécnico do Porto, R. Dr. António Bernardino de Almeida 431, 4200-072, Porto, Portugal. han@isep.ipp.pt.ORCID https://orcid.org/0000-0002-1472-8866
Elisa KeatingDepartment of Biomedicine - Unit of Biochemistry, Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.ORCID https://orcid.org/0000-0002-3904-9907
Virginia Cruz FernandesREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Politécnico do Porto, R. Dr. António Bernardino de Almeida 431, 4200-072, Porto, Portugal.ORCID https://orcid.org/0000-0003-3979-7523
Cristina Delerue-MatosREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Politécnico do Porto, R. Dr. António Bernardino de Almeida 431, 4200-072, Porto, Portugal.ORCID https://orcid.org/0000-0002-3924-776X

Funding

Fundação para a Ciência e a Tecnologia SFRH/BD/111942/2015Fundação para a Ciência e a Tecnologia SFRH/BPD/109153/2015Fundação para a Ciência e a Tecnologia UID/IC/4255/2019Fundação para a Ciência e a Tecnologia UID/QUI/50006/2019
6 · The paper itself

Abstract

An electrochemical magnetic immunosensing strategy was developed for the determination of HER2-ECD, a breast cancer biomarker, and breast cancer cells in human serum. A sandwich assay was performed on carboxylic acid-functionalized magnetic beads (MBs) using a screen-printed carbon electrode (SPCE) as transducer surface. The affinity process was detected using electroactive labels; core/shell streptavidin-modified CdSe@ZnS Quantum Dots (QDs). Cd

Indexed as

Biomarkers, TumorElectrochemical TechniquesFemaleHumansQuantum DotsBiomarkers, TumorBreast cancerCancer cellsElectrochemical immunoassayHER2-ECDMagnetic beadsQuantum dots

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.