Evidence map›Paper›PMID 32088759›Full record

ArticleApplied microbiology and biotechnology2020

A novel DNA methylation motif identified in Bacillus pumilus BA06 and possible roles in the regulation of gene expression.

Gang Liu, Yang-Mei Jiang, Yong-Cheng Liu, Lin-Li Han, Hong Feng

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Genome Sequence ofMicroorganisms · 2022
    Article
  3. Modern epigenetics methods in biological research.Methods (San Diego, Calif.) · 2021
    Review
  4. Empirical Comparison and Analysis of Web-Based DNAMolecular therapy. Nucleic acids · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gang LiuKey Laboratory of Bio-resources and Eco-environment, Ministry of Education; Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, Sichuan, People's Republic of China.
Yang-Mei JiangKey Laboratory of Bio-resources and Eco-environment, Ministry of Education; Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, Sichuan, People's Republic of China.
Yong-Cheng LiuKey Laboratory of Bio-resources and Eco-environment, Ministry of Education; Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, Sichuan, People's Republic of China.
Lin-Li HanKey Laboratory of Bio-resources and Eco-environment, Ministry of Education; Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, Sichuan, People's Republic of China.
Hong FengKey Laboratory of Bio-resources and Eco-environment, Ministry of Education; Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, Sichuan, People's Republic of China. hfeng@scu.edu.cn.ORCID http://orcid.org/0000-0001-6917-4250
Sichuan University · CN

Funding

Major Research Plan 31171204
6 · The paper itself

Abstract

Single-molecule real-time (SMRT) sequencing can be used to identify a wide variety of chemical modifications of the genome, such as methylation. Here, we applied this approach to identify N6-methyl-adenine (m6A) and N4-methyl-cytosine (m4C) modification in the genome of Bacillus pumilus BA06. A typical methylation recognition motif of the type I restriction-modification system (R-M), 5'-TC

Indexed as

DNA MethylationGene Expression Regulation, BacterialGenome, BacterialNucleotide MotifsBacillus pumilusDNA, BacterialMetabolic Networks and PathwaysDNA, BacterialBacillus pumilusDNA methyltransferaseMethylomeSingle-molecule real-time sequencingType I methylation motif

Identifiers

PMID32088759
OpenAlexW3008008637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.