Evidence map›Paper›PMID 32088662›Full record

ReviewCurrent opinion in neurobiology2020

Cortical synaptic architecture supports flexible sensory computations.

Benjamin Scholl, David Fitzpatrick

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Principles of cortical interactions in modular recurrent networks.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Neural signature of flexible coding in prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Article
  9. Clustered Intrinsic Connections: Not a Single System.Frontiers in systems neuroscience · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Benjamin SchollMax Planck Florida Institute, 1 Max Planck Way, Jupiter, FL USA. Electronic address: Ben.Scholl@mpfi.org.
David FitzpatrickMax Planck Florida Institute, 1 Max Planck Way, Jupiter, FL USA.

Funding

The Development of Direction Selectivity in Visual CortexR01EY011488 · NEI · MAX PLANCK FLORIDA CORPORATION · PI FITZPATRICK, DAVID · 1996 to 2025
$10.6M
Functional Synaptic Architecture of Visual CortexR01EY006821 · NEI · MAX PLANCK FLORIDA CORPORATION · PI FITZPATRICK, DAVID · 1987 to 2020
$7.2M
Principles of presynaptic networks for single layer 2/3 neurons in ferret visual cortexK99EY031137 · NEI · MAX PLANCK FLORIDA CORPORATION · PI SCHOLL, BENJAMIN KYLE · 2020 to 2021
$216k
NEI NIH HHS K99 EY031137NEI NIH HHS R01 EY006821NEI NIH HHS R01 EY011488
6 · The paper itself

Abstract

Establishing the fundamental principles that underlie the integration of excitatory and inhibitory presynaptic input populations is crucial to understanding how individual cortical neurons transform signals from peripheral receptors. Here we review recent studies using novel tools to examine the functional properties of excitatory synaptic inputs and the tuning of excitation and inhibition onto individual neurons. New evidence challenges existing synaptic connectivity rules and suggests a more complex functional synaptic architecture that supports a broad range of operations, enabling single neurons to encode multiple sensory features and flexibly shape their computations in the face of diverse sensory input.

Indexed as

NeuronsSynapses

Identifiers

PMID32088662
PMCPMC8080306

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.