ReviewCurrent opinion in microbiology2020
Microbe-microbe interactions during Clostridioides difficile infection.
Review in Current opinion in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Bacillus velezensis mitigates chronic LPS-induced lung injury of broilers via microbiota-driven isoflavone production and NF-κB/PPAR-γ axis modulation.Journal of animal science and biotechnology · 2026Article
- Dynamics of the microbiota in patients with Clostridioides difficile: Recurrence, treatment, sex, and immunosuppression.PLoS pathogens · 2026Article
- Caffeic acid phenethyl ester protectseLife · 2025Article
- Global, regional, and national incidence and mortality for enteric infections from 1990 to 2019.BMC public health · 2025Article
- Article
- RelQ-mediated alarmone signalling regulates growth, stress-induced biofilm formation and spore accumulation inMicrobiology (Reading, England) · 2024Article
- RelQ-mediated alarmone signaling regulates growth, sporulation, and stress-induced biofilm formation inbioRxiv : the preprint server for biology · 2024Article
- Review
- Evolutionary modeling suggests that addictions may be driven by competition-induced microbiome dysbiosis.Communications biology · 2023Article
- Transmission of the Potential Pathogen Atypical Enteropathogenic Escherichia coli by Fecal Microbiota Transplant.Gastroenterology · 2023Article
- Article
- Microbial Interdomain Interactions Delineate the Disruptive Intestinal Homeostasis in Clostridioides difficile Infection.Microbiology spectrum · 2022Article
- Article
- Concurrent and Subsequent Co-Infections ofMicroorganisms · 2022Review
- Effect of cryopreservation medium conditions on growth and isolation of gut anaerobes from human faecal samples.Microbiome · 2022Article
- Article
- Clostridioides difficile toxins: mechanisms of action and antitoxin therapeutics.Nature reviews. Microbiology · 2022Review
- Effect ofBiomedicines · 2022Review
- "Bacterial Consortium": A Potential Evolution of Fecal Microbiota Transplantation for the Treatment ofBioMed research international · 2022Article
- Total glycosides contribute to the anti-diarrheal effects of Qiwei Baizhu PowderFrontiers in cellular and infection microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Clostridioides difficile is the leading cause of hospital-acquired gastrointestinal infections and a major public health burden in the United States. C. difficile infection causes a spectrum of disease from mild diarrhea to severe complications such as pseudomembranous colitis, toxic megacolon and death. This broad range of disease is only partially explained by bacterial genetic factors, host genetics, comorbidities and previous drug exposures. Another important factor is the gut microbiome, the disruption of which results in a loss of colonization resistance to C. difficile. Here, we review how gut microbiota and their metabolites impact C. difficile virulence and influence disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.