ArticleThe Journal of allergy and clinical immunology2020
Transcriptome-wide and differential expression network analyses of childhood asthma in nasal epithelium.
Open access · greenAbstract readLetter
In one paragraph
Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
2.4field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Violence-Related Distress, Nasal Epithelial Gene Expression, and T17-High Asthma in Youth.Pediatric pulmonology · 2026Pooled it
- Long-Term PMAnnals of the American Thoracic Society · 2025Pooled it
- Differential gene expression in nasal airway epithelium from overweight or obese youth with asthma.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022Pooled it
- Exposure to violence, chronic stress, nasal DNA methylation, and atopic asthma in children.Pediatric pulmonology · 2021Pooled it
- A genome-wide association study of severe asthma exacerbations in Latino children and adolescents.The European respiratory journal · 2021Pooled it
- eQTM (expression quantitative trait methylation) Atlas: a comprehensive resource of over 11 million DNA methylation-gene expression associations through across 11 tissues and 4 diseases.bioRxiv : the preprint server for biology · 2026Article
- Transcriptome-wide association study of sex effects identifies sex-specific nasal epithelial gene expression profiles for total IgE.The Journal of allergy and clinical immunology · 2026Article
- Estimating in silico causal effects of DNA methylation on gene expression through genetic anchors in airway epithelium in asthma.Science advances · 2026Article
- Integrating genomics as clinical biomarkers in pediatric pulmonology.Pediatric pulmonology · 2025Review
- Nasal Epithelium Transcriptomics Predict Clinical Response to Elexacaftor/Tezacaftor/Ivacaftor.American journal of respiratory cell and molecular biology · 2024Article
- MOSES: a methylation-based gene association approach for unveiling environmentally regulated genes linked to a trait or disease.Clinical epigenetics · 2024Article
- Long-term alterations in lung epithelial cells after EL-RSV infection exacerbate allergic responses through IL-1β-induced pathways.Mucosal immunology · 2024Article
- Nasal epithelial gene expression and total IgE in children and adolescents with asthma.The Journal of allergy and clinical immunology · 2024Article
- Cis- and trans-eQTM analysis reveals novel epigenetic and transcriptomic immune markers of atopic asthma in airway epithelium.The Journal of allergy and clinical immunology · 2023Article
- Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key drivers.Genome medicine · 2023Article
- Asthma Exacerbations: The Genes Behind the Scenes.Journal of investigational allergology & clinical immunology · 2023Review
- Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma.Cell genomics · 2023Article
- Asthma in the Americas: An Update: A Joint Perspective from the Brazilian Thoracic Society, Canadian Thoracic Society, Latin American Thoracic Society, and American Thoracic Society.Annals of the American Thoracic Society · 2022Review
- The Predictive Role of Biomarkers and Genetics in Childhood Asthma Exacerbations.International journal of molecular sciences · 2021Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 3 institutions in 3 countries.
Erick FornoDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa.
Rong ZhangDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; Department of Statistics, University of Pittsburgh, Pittsburgh, Pa.
Yale JiangDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; School of Medicine, Tsinghua University, Beijing, China.
Soyeon KimDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa.
Qi YanDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa.
Zhao RenDepartment of Statistics, University of Pittsburgh, Pittsburgh, Pa.
Yueh-Ying HanDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa.
Nadia BoutaouiDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa.
Franziska RosserDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa.
Daniel E WeeksDepartment of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pa.
Edna Acosta-PérezBehavioral Sciences Research Institute, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico.
Angel Colón-SemideyDepartment of Pediatrics, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico.
María AlvarezDepartment of Pediatrics, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico.
Glorisa CaninoBehavioral Sciences Research Institute, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico.
Wei ChenDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa.
Juan C CeledónDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa. Electronic address: juan.celedon@chp.edu.
University of Pittsburgh · USUniversity of Puerto Rico, Medical Sciences Campus · PRChildren's Hospital of Pittsburgh · US
Funding
Epigenetic Variation and Childhood Asthma in Puerto RicansR01HL117191 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2013 to 2020
$5.8MGenes, Home Allergens and Asthma Puerto Rican ChildrenR01HL079966 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2006 to 2010
$3.8MObesity and Childhood Asthma: The Role of Adipose TissueR01HL149693 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORNO, ERICK · 2020 to 2024
$3.0MPittsburgh Training Grant in Pediatric Pulmonary MedicineT32HL129949 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Juan Carlos Celedon · 2016 to 2026
$2.9MExposure to violence, epigenetic variation, and asthma in Puerto Rican childrenR01MD011764 · NIMHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2017 to 2020
$1.3MObesity and Asthma Subphenotypes and Underlying Genetic and Genomic PathwaysK08HL125666 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORNO, ERICK · 2015 to 2018
$589kNHLBI NIH HHS K08 HL125666NHLBI NIH HHS R01 HL079966NHLBI NIH HHS R01 HL117191NHLBI NIH HHS R01 HL149693NHLBI NIH HHS T32 HL129949NIMHD NIH HHS R01 MD011764
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdolescentAdultAsthmaCase-Control StudiesChildFemaleGene Expression ProfilingHumansImmunoglobulin EMaleNasal MucosaTranscriptomeYoung AdultImmunoglobulin E
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.