Evidence map›Paper›PMID 32088306›Full record

ArticleThe Journal of allergy and clinical immunology2020

Glycolipid-mediated basophil activation in alpha-gal allergy.

Onyinye I Iweala, Shailesh K Choudhary, Claire T Addison, Cole J Batty, Camille M Kapita, Claire Amelio, Alexander J Schuyler, Shenglou Deng, Eric M Bachelder, Kristy M Ainslie and 3 more

Open access · greenAbstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  7. The Role ofPathogens (Basel, Switzerland) · 2025
    Article
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  14. Annals of internal medicine. Clinical cases · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Onyinye I IwealaDepartment of Medicine, Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Chapel Hill, NC; Department of Pediatrics, University of North Carolina Food Allergy Initiative, Division of Allergy, Immunology and Rheumatology, Chapel Hill, NC. Electronic address: onyinye.iweala@med.unc.edu.
Shailesh K ChoudharyDepartment of Medicine, Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Chapel Hill, NC.
Claire T AddisonDepartment of Medicine, Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Chapel Hill, NC.
Cole J Battythe Eshelman School of Pharmacy, Division of Pharmacoengineering and Molecular Pharmaceutics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Camille M KapitaDepartment of Medicine, Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Chapel Hill, NC.
Claire AmelioDepartment of Medicine, Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Chapel Hill, NC.
Alexander J Schuylerthe Division of Allergy & Clinical Immunology, University of Virginia, Charlottesville, Va.
Shenglou Dengthe Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah.
Eric M Bachelderthe Eshelman School of Pharmacy, Division of Pharmacoengineering and Molecular Pharmaceutics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Kristy M Ainsliethe Eshelman School of Pharmacy, Division of Pharmacoengineering and Molecular Pharmaceutics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Paul B Savagethe Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah.
Patrick J Brennanthe Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Scott P ComminsDepartment of Medicine, Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Chapel Hill, NC; Department of Pediatrics, University of North Carolina Food Allergy Initiative, Division of Allergy, Immunology and Rheumatology, Chapel Hill, NC.
University of North Carolina at Chapel Hill · USBrigham Young University · USBrigham and Women's Hospital · USUniversity of Virginia · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
RESEARCH TRAINING IN ALLERGY AND CLINICAL IMMUNOLOGYT32AI007062 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David B. Peden, John W. Sleasman · 1985 to 2026
$6.1M
Understanding alpha-gal red meat allergyR01AI135049 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott Palmer Commins · 2018 to 2026
$5.1M
Self and dietary lipid antigens for invariant natural killer T cellsK08AI102945 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BRENNAN, PATRICK JOSEPH · 2013 to 2016
$736k
Delayed Anaphylaxis to Mammalian Meat caused by IgE Ab to alpha-galR56AI113095 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COMMINS, SCOTT PALMER · 2014 to 2014
$390k
NCI NIH HHS P30 CA016086NIAID NIH HHS K08 AI102945NIAID NIH HHS R01 AI135049NIAID NIH HHS R56 AI113095NIAID NIH HHS T32 AI007062
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Allergensalpha-GalactosidaseAntigens, CD1dBasophil Degranulation TestBasophilsCell DegranulationCells, CulturedFood HypersensitivityGlycolipidsHumansImmunoglobulin ERed MeatAllergensalpha-GalactosidaseAntigens, CD1dGLA protein, humanGlycolipidsImmunoglobulin E

Identifiers

PMID32088306
PMCPMC7670280
OpenAlexW3006955892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.