Observational studyCritical care (London, England)2020
Prognostic value of venous blood analysis at the start of CPR in non-traumatic out-of-hospital cardiac arrest: association with ROSC and the neurological outcome.
Observational study in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04571281 (Dynamics of the Capillary Lactate Levels in Patients With Out-of-hospital Cardiac Arrest), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dynamics of the Capillary Lactate Levels in Patients With Out-of-hospital Cardiac Arrest
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The use and impact of prehospital blood lactate measurements in acute non-traumatic patients: a systematic review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Pooled it
- Article
- Dynamic changes in lactate and blood acid-base status during cardiopulmonary resuscitation and clinical outcomes in adult cardiac arrest patients: a prospective study.Resuscitation plus · 2026Article
- Potential return of spontaneous circulation in Japanese out-of-hospital cardiac arrest patients with pseudo-pulseless electrical activity: a post hoc analysis of a prospective multicentric study.Resuscitation plus · 2026Article
- Prehospital prediction of survival after out-of-hospital cardiac arrest using point-of-care testing and vital signs: a prospective, multinational study.Scientific reports · 2026Article
- Association between early arterial pH, base excess and lactate and 24-h mortality and neurological outcomes after cardiac arrest and cardiopulmonary resuscitation: a translational study.Resuscitation plus · 2026Article
- Association between base excess level at hospital arrival and neurological outcomes in adult out-of-hospital cardiac arrest: A multicentre cohort study.Resuscitation plus · 2025Article
- Initial arterial pH predicts survival of out-of-hospital cardiac arrest in South Korea.Acute and critical care · 2025Article
- Predictive value of venous bicarbonate levels for survival to hospital discharge in out-of-hospital cardiac arrest patients.International journal of emergency medicine · 2025Article
- Reducing Time Taken to Gather Equipment for Venepuncture and Cannulation: A Quality Improvement Project.Cureus · 2024Article
- Intra-arrest blood-based biomarkers for out-of-hospital cardiac arrest: A scoping review.Journal of the American College of Emergency Physicians open · 2024Article
- Prognostic value of arterial carbon dioxide tension during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients receiving extracorporeal resuscitation.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- Dynamics of Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest.Medicina (Kaunas, Lithuania) · 2023Observational
- Prediction of return of spontaneous circulation in out-of-hospital cardiac arrest with non-shockable initial rhythm using point-of-care testing: a retrospective observational study.World journal of emergency medicine · 2023Article
- Prehospital qSOFA, mSOFA, and NEWS2 performance for sepsis prediction: A prospective, multi-center, cohort study.Frontiers in medicine · 2023Article
- Prediction Models for Return of Spontaneous Circulation in Patients with Cardiac Arrest: A Systematic Review and Critical Appraisal.Emergency medicine international · 2023Review
- Dynamic changes in arterial blood gas during cardiopulmonary resuscitation in out-of-hospital cardiac arrest.Scientific reports · 2021Observational
- Prognostic value of venous blood analysis at the start of CPR in non-traumatic out-of-hospital cardiac arrest: association with ROSC and the neurological outcome: do not forget the no-flow influence!Critical care (London, England) · 2020Article
- Resuscitation for Cardiac Arrest and Postcardiac Arrest Care.Emergency medicine international · 2020Article
- Elective Initial Blood Testing for the Neurological Outcomes of Pediatric Out-of-Hospital Cardiac Arrests.Pediatrics international : official journal of the Japan Pediatric SocietyArticle
Corrections and comments
- Commented on by
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe knowledge of new prognostic factors in out-of-hospital cardiac arrest (OHCA) that can be evaluated since the beginning of cardiopulmonary resuscitation (CPR) manoeuvres could be helpful in the decision-making process of prehospital care. We aim to identify metabolic variables at the start of advanced CPR at the scene that may be associated with two main outcomes of CPR (recovery of spontaneous circulation (ROSC) and neurological outcome).
methodsProspective observational study of all non-traumatic OHCA in patients older than 17 years assisted by emergency medical services (EMS), with doctor and nurse on board, between January 2012 and December 2017. Venous blood gases were sampled upon initially obtaining venous access to determine the initial values of pH, pCO
resultsWe included 1552 patients with OHCA with blood test data in a 6-year period. ROSC was achieved in 906 cases (58.4%), and good neurological recovery at 30 days (CPC I-II) occurred in 383 cases (24.68%). In multivariate analysis, we found a significant relationship between non-recovery of spontaneous circulation (no-ROSC) and low pH levels (adjusted odds ratio (OR) 0.03 (0.002-0.59), p = 0.020), high pCO
conclusionThere is a significant relationship between severe alterations of venous blood-gas variables and potassium at the start of CPR of non-traumatic OHCA and low-ROSC rate and neurological prognosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.