ArticleActa veterinaria Scandinavica2020
Encephalitozoon cuniculi infection in farmed rabbits in Egypt.
Article in Acta veterinaria Scandinavica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Guideline
- Microsporidia: evolution, infection mechanisms and host impact.Nature reviews. Microbiology · 2026Review
- Clinical Molecular Investigation of Encephalitozoon cuniculi in Pet Rabbits: Early Detection of Potential Risk for Animal and Human Infection.Veterinary medicine and science · 2026Article
- Encephalitozoonosis in Pet Rabbits: Epidemiology, Pathogenesis, Immunology and Consensus on Clinical Management.Animals : an open access journal from MDPI · 2026Review
- Comparative Evaluation of the Serological Methods and the Molecular Genetics Techniques for the Diagnosis ofMicroorganisms · 2025Article
- Antemortem and Postmortem Diagnosis ofPathogens (Basel, Switzerland) · 2024Article
- Renal abscess in a Lionhead rabbit due toOpen veterinary journal · 2024Article
- The Prevalence ofMicroorganisms · 2024Article
- Article
- Molecular Detection of Microsporidia in Rabbits (Biology · 2022Article
- A Review ofPathogens (Basel, Switzerland) · 2022Review
- A multidisciplinary review about Encephalitozoon cuniculi in a One Health perspective.Parasitology research · 2022Review
- Alternatives to antibiotics for organic poultry production: types, modes of action and impacts on bird's health and production.Poultry science · 2022Review
- Pre-mating plasma prolactin profile affects California doe rabbit reproductive performance.Saudi journal of biological sciences · 2022Article
- A comparative study among dietary supplementations of antibiotic, grape seed and chamomile oils on growth performance and carcass properties of growing rabbits.Saudi journal of biological sciences · 2022Article
- Chronic Infections in Mammals Due to Microsporidia.Experientia supplementum (2012) · 2022Article
- Sparse Evidence forPathogens (Basel, Switzerland) · 2021Article
- International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Rabbit.Journal of toxicologic pathology · 2021Review
- Zoonotic Microsporidia in Wild Lagomorphs in Southern Spain.Animals : an open access journal from MDPI · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEncephalitozoon cuniculi is an important microsporidian parasite with zoonotic potential. The present study highlights the impact of encephalitozoonosis on rabbit health in Egypt. Three rabbit farms in Giza, with a total of 16,400 rabbits were investigated due to occurrence of rabbits displaying clinical signs consistent with encephalitozoonosis.
resultsClinical signs observed during a 4 months observation period in 2018 included vestibular disease, paresis, limb paralysis, cataracts, phacoclastic uveitis, frequent urination, marked decrease in body weight and in some pregnant females, also repeated abortions. The total morbidity rates in adult and young rabbits were 76.7% and 81.5%, respectively. The highest mortality rate was recorded in offspring (12.3%), followed by dams (5.6%), and the lowest recorded mortality rate was in males (0.04%). Post-mortem findings included enteritis, pale enlarged kidneys, congested leptomeninges, focal brain necrosis, and endometrial congestion. Histopathological examination revealed nonsuppurative meningoencephalitis and glial nodules with central necrosis in the brain, vacuolation and necrosis of renal tubular epithelium, and corneal ulceration and ruptured lens capsule with fragmentation of lenticular fibres. E. cuniculi were observed in the brain, retinal ganglion cells, kidneys, and liver. Transmission electron microscopy examination revealed the presence of different developmental stages of E. cuniculi in the brain and kidney. Presence of E. cuniculi was confirmed by conventional polymerase chain reaction using a universal 16S gene for Encephalitozoon spp. followed by sequencing and sequence analysis.
conclusionsThe presence of E. cuniculi in rabbits was confirmed at three farms in Egypt. Nervous signs and ocular lesions were the most predominant findings in these farms.
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Registered trials
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