ReviewJournal of cachexia, sarcopenia and muscle2020
Bone in heart failure.
Review in Journal of cachexia, sarcopenia and muscle, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07094568 (Comparative Investigation of Changes in Body Composition and Bone Turnover Markers in People With Obesity After Treatment With Tirzepatide Versus Liraglutide. A Prospective Cohort Study.), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Investigation of Changes in Body Composition and Bone Turnover Markers in People With Obesity After Treatment With Tirzepatide Versus Liraglutide. A Prospective Cohort Study.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Bidirectional association between cardiovascular disease and hip fracture: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- The association between heart failure and risk of fractures: Pool analysis comprising 260,410 participants.Frontiers in cardiovascular medicine · 2022Pooled it
- The Association of Bone Turnover Markers with Muscle Function, Falls, and Frailty in Older Women in Long-Term Care.The Journal of frailty & aging · 2023Trial
- Impact of Beta-Blocker Therapy for Cardiovascular Diseases on Bone Healing Following Fracture Surgery.Calcified tissue international · 2026Review
- Underlying Mechanisms of Osteoporosis in the Context of Multimorbidity: Clinical Challenges and Management Strategies.Nutrients · 2026Review
- Screening and risk factor analysis of osteoporosis in elderly patients with chronic heart failure.European journal of medical research · 2026Article
- Low skeletal muscle index combined with reduced bone density increases mortality rate in older adults with heart failure.Aging clinical and experimental research · 2025Article
- Association Between Serum Apolipoprotein B and Bone Mineral Density and the Effects of Cardiovascular Disease Mediation: Results From the NHANES 2011-2016 and a Mendelian Randomization Study.Reviews in cardiovascular medicine · 2025Article
- RBFOX2 induces osteogenic differentiation by Jph2 expression in MC3T3-E1 preosteoblast cells.Molecular biology reports · 2025Article
- Can N-terminal pro-B-type natriuretic peptide concentration on admission predict the functional independence measure at discharge in patients aged 75 years or older with postoperative proximal femur fracture?Journal of physical therapy science · 2025Article
- Prevalence and prognostic impact of bone disease in chronic heart failure with reduced ejection fraction.ESC heart failure · 2024Article
- Extent of Abdominal Aortic Calcification Is Associated With Incident Rapid Weight Loss Over 5 Years: The Perth Longitudinal Study of Ageing Women.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
- Vitamin D Deficiency and Cardiovascular Mortality: Retrospective Analysis "Siena Osteoporosis" Cohort.Nutrients · 2023Article
- Bone Mineral Density, Trabecular Bone Score and Fractures in Patients Hospitalized for Heart Failure.Journal of bone metabolism · 2023Article
- Article
- Cardiovascular Disease Diagnosis from DXA Scan and Retinal Images Using Deep Learning.Sensors (Basel, Switzerland) · 2022Article
- A year in heart failure: an update of recent findings.ESC heart failure · 2021Review
- Bone in heart failure.Journal of cachexia, sarcopenia and muscle · 2020Review
- Skeletal consequences of heart failure.Women's health (London, England)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is an increasing interest in osteoporosis and reduced bone mineral density affecting not only post-menopausal women but also men, particularly with coexisting chronic diseases. Bone status in patients with stable chronic heart failure (HF) has been rarely studied so far. HF and osteoporosis are highly prevalent aging-related syndromes that exact a huge impact on society. Both disorders are common causes of loss of function and independence, and of prolonged hospitalizations, presenting a heavy burden on the health care system. The most devastating complication of osteoporosis is hip fracture, which is associated with high mortality risk and among those who survive, leads to a loss of function and independence often necessitating admission to long-term care. Current HF guidelines do not suggest screening methods or patient education in terms of osteoporosis or osteoporotic fracture. This review may serve as a solid base to discuss the need for bone health evaluation in HF patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.