Evidence map›Paper›PMID 32087603›Full record

ArticleAging2020

Development and validation of a RNA binding protein-associated prognostic model for lung adenocarcinoma.

Wei Li, Li-Na Gao, Pei-Pei Song, Chong-Ge You

Erratum issuedOpen access · greenAbstract readValidation Study
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wei LiLaboratory Medicine Center, Lanzhou University Second Hospital, Lanzhou 730030, China.
Li-Na GaoLaboratory Medicine Center, Lanzhou University Second Hospital, Lanzhou 730030, China.
Pei-Pei SongLaboratory Medicine Center, Lanzhou University Second Hospital, Lanzhou 730030, China.
Chong-Ge YouLaboratory Medicine Center, Lanzhou University Second Hospital, Lanzhou 730030, China.
Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA binding proteins (RBPs) dysregulation have been reported in various malignant tumors and associated with the occurrence and development of cancer. However, the role of RBPs in lung adenocarcinoma (LUAD) is poorly understood. We downloaded the RNA sequencing data of LUAD from the Cancer Genome Atlas (TCGA) database and determined the differently expressed RBPs between normal and cancer tissues. The study then systemically investigated the expression and prognostic value of these RBPs by a series of bioinformatics analysis. A total of 223 differently expressed RBPs were identified, including 101 up-regulated and 122 down-regulated RBPs. Eight RBPs (

Indexed as

Gene Expression Regulation, NeoplasticModels, TheoreticalAdenocarcinoma of LungBiomarkers, TumorDatabases, GeneticFemaleHumansLung NeoplasmsMalePrognosisRNA-Binding ProteinsSurvival RateTranscriptomeBiomarkers, TumorRNA-Binding Proteinslung adenocarcinomaoverall survivalprognostic modelRNA binding proteins

Identifiers

PMID32087603
PMCPMC7066909
OpenAlexW3007324275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.