ReviewCurrent opinion in insect science2020
Signal transduction in the early Drosophila follicle stem cell lineage.
Review in Current opinion in insect science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- Cytokinesis genes regulate ring canal patterning and follicle cell differentiation inbioRxiv : the preprint server for biology · 2026Article
- Germline cysts require Ecdysone receptor for proper timing of encapsulation in the Drosophila ovary.Developmental biology · 2026Article
- The Drosophila ovary produces two waves of adult follicles and a previously unreported pupal wave that turns over.Development (Cambridge, England) · 2026Article
- Article
- Hh and EGFR-Ras signaling promote distinct steps of tumor progression in the Drosophila follicle epithelium.Nature communications · 2026Article
- A decline in follicle cell function is a major driver ofbioRxiv : the preprint server for biology · 2026Article
- Starve-Feed Cycles Direct Quiescence to Proliferation Transitions inbioRxiv : the preprint server for biology · 2026Article
- Independent signaling pathways provide a fail-safe mechanism to prevent tumorigenesis.bioRxiv : the preprint server for biology · 2025Article
- The pattern of the follicle cell diversification in ovarian follicles of the true fruit flies, Tephritidae.Journal of anatomy · 2024Article
- Mechanical stimulation from the surrounding tissue activates mitochondrial energy metabolism in Drosophila differentiating germ cells.Developmental cell · 2023Article
- Single-cell expression profile of Drosophila ovarian follicle stem cells illuminates spatial differentiation in the germarium.BMC biology · 2023Article
- Specialized cells that sense tissue mechanics to regulate Drosophila morphogenesis.Developmental cell · 2023Article
- Sequential events during the quiescence to proliferation transition establish patterns of follicle cell differentiation in the Drosophila ovary.Biology open · 2023Article
- Polarity Events in theFrontiers in cell and developmental biology · 2022Review
- Distinct roles of Bendless in regulating FSC niche competition and daughter cell differentiation.Development (Cambridge, England) · 2021Article
- A single-cell atlas reveals unanticipated cell type complexity inGenome research · 2021Article
- Transcriptomic analysis of feminizing somatic stem cells in the Drosophila testis reveals putative downstream effectors of the transcription factor Chinmo.G3 (Bethesda, Md.) · 2021Article
- Orphan nuclear receptor ftz-f1 (NR5A3) promotes egg chamber survival in the Drosophila ovary.G3 (Bethesda, Md.) · 2021Article
- Nuclear receptors linking physiology and germline stem cells in Drosophila.Vitamins and hormones · 2021Review
- Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The follicle stem cell (FSC) lineage in the Drosophila ovary is a highly informative model of in vivo epithelial stem cell biology. Studies over the past 30 years have identified roles for every major signaling pathway in the early FSC lineage. These pathways regulate a wide variety of cell behaviors, including self-renewal, proliferation, survival and differentiation. Studies of cell signaling in the follicle epithelium have provided new insights into how these cell behaviors are coordinated within an epithelial stem cell lineage and how signaling pathways interact with each other in the native, in vivo context of a living tissue. Here, we review these studies, with a particular focus on how these pathways specify differences between the FSCs and their daughter cells. We also describe common themes that have emerged from these studies, and highlight new research directions that have been made possible by the detailed understanding of the follicle epithelium.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.