Evidence map›Paper›PMID 32087449›Full record

ArticlePsychiatry research2020

Sleep disturbance and sleep-related impairment in psychotic disorders are related to both positive and negative symptoms.

Jack J Blanchard, Alexandra Andrea, Ryan D Orth, Christina Savage, Melanie E Bennett

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jack J BlanchardDepartment of Psychology, University of Maryland, College Park, MD 20742, USA. Electronic address: jblancha@umd.edu.
Alexandra AndreaDepartment of Psychology, University of Maryland, College Park, MD 20742, USA.
Ryan D OrthDepartment of Psychology, University of Maryland, College Park, MD 20742, USA.
Christina SavageDepartment of Psychology, University of Maryland, College Park, MD 20742, USA.
Melanie E BennettDepartment of Psychiatry, University of Maryland School of Medicine, 737 W. Lombard Street, Suite 551 Baltimore, MD 21201, USA; Department of Psychiatry, Baltimore VA Medical Center, 10 North Greene Street, Baltimore, MD 21201, USA.
University of Maryland, College Park · USUniversity of Maryland, Baltimore · US

Funding

Understanding Social Affiliative Deficits in PsychopathologyR01MH110462 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI BLANCHARD, JACK J. · 2016 to 2019
$2.3M
NIMH NIH HHS R01 MH110462
6 · The paper itself

Abstract

A large literature indicates that sleep disturbances are associated with paranoia and other positive symptoms in psychotic disorders. However, few studies have examined the potential association between sleep disturbances and negative symptoms and the results have been inconsistent. The current study examined the hypothesis that sleep problems would be associated with more severe positive and negative symptoms in a transdiagnostic sample of individuals with psychosis (N = 90). Further, we examined whether sleep would be related to negative symptoms above and beyond the contribution of paranoia, other positive symptoms, and depression-anxiety. Results replicated prior research in finding that both sleep disturbance and sleep-related impairment were related to more severe paranoia, other positive symptoms and depression-anxiety. Consistent with our hypothesis, more severe sleep disturbance and sleep-related impairment were related to greater negative symptoms; this was evident across both motivation-pleasure deficits and diminished expression. Sleep variables remained significantly related to motivation-pleasure deficits even after controlling for other non-negative symptoms. These results indicate the broad symptom impact of sleep disturbances and may suggest a novel treatment target to improve negative symptoms.

Indexed as

AnxietyClinical symptomsDepressionPsychosisSleep problemsTransdiagnostic

Identifiers

PMID32087449
PMCPMC7416463
OpenAlexW3005091864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.