Evidence map›Paper›PMID 32086949›Full record

ArticleJournal of the American Geriatrics Society2020

Medical Doctors and Dementia: A Longitudinal Study.

Maria Vassilaki, Jeremy A Syrjanen, Walter K Kremers, Philip T Hagen, David S Knopman, Michelle M Mielke, Yonas E Geda, Rabe E Alhurani, Mary M Machulda, Rosebud O Roberts and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Maria VassilakiDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-8328-136X
Jeremy A SyrjanenDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Walter K KremersDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Philip T HagenDepartment of Preventive Medicine, Mayo Clinic, Rochester, Minnesota.
David S KnopmanDepartment of Neurology, Mayo Clinic, Rochester, Minnesota.
Michelle M MielkeDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Yonas E GedaDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Rabe E AlhuraniDepartment of Neurology, Mayo Clinic, Rochester, Minnesota.
Mary M MachuldaDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.
Rosebud O RobertsDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Ronald C PetersenDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · USMayo Clinic in Florida · USMayo Clinic in Arizona · US

Funding

SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI BU, GUOJUN · 1999 to 2018
$36.9M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI Walter K. Kremers · 2019 to 2026
$33.5M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Pathways linking neuropsychiatric symptoms with Alzheimer's disease neuroimaging biomarkers and the outcome of incident Mild Cognitive Impairment/ DementiaR01AG057708 · NIA · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI GEDA, YONAS E · 2018 to 2022
$1.7M
NIA NIH HHS P30 AG062677NIA NIH HHS P50 AG016574NIA NIH HHS R01 AG034676NIA NIH HHS R01 AG057708NIA NIH HHS U01 AG006786NIH HHS P50 AG016574NIH HHS R01 AG034676NIH HHS U01 AG006786
6 · The paper itself

Abstract

objectiveTo examine the association between being a medical doctor (MD) and the risk of incident dementia.

designCohort study.

settingOlmsted County, Minnesota.

participantsA total of 3460 participants (including 104 MDs), aged 70 years or older, of the population-based Mayo Clinic Study of Aging. MEASUREMENTS: Participants were randomly selected from the community and had comprehensive cognitive evaluations at baseline and approximately every 15 months to assess for diagnosis of dementia. For participants who withdrew from the follow-up, dementia diagnosis was also assessed using information available in their medical record. The associations were examined using Cox proportional hazards models, adjusting for sex, education, and apolipoprotein E ε4, using age as the time scale.

resultsMDs were older (vs "general population"), and most were males (93.3%). MDs without dementia at baseline did not have a significantly different risk for incident dementia (hazard ratio = 1.12; 95% confidence interval = 0.69-1.82; P = .64) compared to the general population.

conclusionsAlthough the study includes a small number of older, mainly male, MDs, it provides a preliminary insight on cognitive health later in life in MDs, while most previous studies examine the health of younger MDs. Larger longitudinal studies are needed to examine these associations and investigate if associations are modified by sex. J Am Geriatr Soc 68:1250-1255, 2020.

Indexed as

AgingIndependent LivingAgedAged, 80 and overDementiaFemaleHumansInterviews as TopicLongitudinal StudiesMaleMiddle AgedMinnesotaPhysiciansProspective Studiescohort studydementiamedical doctors

Identifiers

PMID32086949
PMCPMC7649053
OpenAlexW3008711347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.