ArticleIntensive care medicine experimental2020
Real-time effects of PEEP and tidal volume on regional ventilation and perfusion in experimental lung injury.
Article in Intensive care medicine experimental, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05812365 (Best End-Expiratory and Driving-Pressure for Individualized Flow Controlled Ventilation in Patients With COPD - an Observational Study.), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Best End-Expiratory and Driving-Pressure for Individualized Flow Controlled Ventilation in Patients With COPD - an Observational Study.
Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Revisiting ventilator-induced lung injury: from mechanical power to immunometabolic interaction.Frontiers in immunology · 2026Review
- Association between ventilation-perfusion matching improvement during initial prone positioning and ICU mortality in patients with moderate to severe ARDS: a prospective two-center study.Annals of intensive care · 2025Article
- First Real-Time Imaging of Acute Effects of Arteriovenous Fistula on Regional Distribution of Pulmonary Perfusion in a Novel Porcine Model.Physiological research · 2025Article
- Real-Time Effects of Disconnection of the Ventilator on Regional Lung Volumes and Ventilation Distribution.Respiratory care · 2024Article
- [Research progress on electrical impedance tomography in pulmonary perfusion].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Review
- Electrical Impedance Tomography Identifies Evolution of Regional Perfusion in a Porcine Model of Acute Respiratory Distress Syndrome.Anesthesiology · 2023Article
- Real-time effects of lateral positioning on regional ventilation and perfusion in an experimental model of acute respiratory distress syndrome.Frontiers in physiology · 2023Article
- Homogenizing effect of PEEP on tidal volume distribution during neurally adjusted ventilatory assist: study of an animal model of acute respiratory distress syndrome.Respiratory research · 2022Article
- Associating local strains to global pressure-volume mouse lung mechanics using digital image correlation.Physiological reports · 2022Article
- Measuring Indirect Radiation-Induced Perfusion Change in Fed Vasculature Using Dynamic Contrast CT.Journal of personalized medicine · 2022Article
- Effects of PEEP on regional ventilation-perfusion mismatch in the acute respiratory distress syndrome.Critical care (London, England) · 2022Article
- Three broad classifications of acute respiratory failure etiologies based on regional ventilation and perfusion by electrical impedance tomography: a hypothesis-generating study.Annals of intensive care · 2021Article
- Unmatched ventilation and perfusion measured by electrical impedance tomography predicts the outcome of ARDS.Critical care (London, England) · 2021Observational
- Targeted lateral positioning decreases lung collapse and overdistension in COVID-19-associated ARDS.BMC pulmonary medicine · 2021Observational
- Physiological mechanism and spatial distribution of increased alveolar dead-space in early ARDS: An experimental study.Acta anaesthesiologica Scandinavica · 2021Article
- A Step Forward toward a Bedside and Timely Monitoring of RegionalAmerican journal of respiratory and critical care medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundReal-time bedside information on regional ventilation and perfusion during mechanical ventilation (MV) may help to elucidate the physiological and pathophysiological effects of MV settings in healthy and injured lungs. We aimed to study the effects of positive end-expiratory pressure (PEEP) and tidal volume (V
methodsOne-hit acute lung injury model was established in 6 piglets by repeated lung lavages (injured group). Four ventilated piglets served as the control group. A randomized sequence of any possible combination of three V
resultsTwo-way interactions between PEEP and group, and V
conclusionsLarge PEEP and V
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.