ArticleSurgical endoscopy2021
Postoperative recurrent laryngeal nerve palsy is associated with pneumonia in minimally invasive esophagectomy for esophageal cancer.
Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Preoperative risk factors for postoperative pneumonia in patients with esophageal cancer: A systematic review and meta-analysis.Surgery today · 2026Pooled it
- Diagnostic performance of transcutaneous laryngeal ultrasound for vocal cord paralysis after esophagectomy: a systematic review and meta-analysis.Esophagus : official journal of the Japan Esophageal Society · 2026Pooled it
- Multicentre randomized clinical trial on robot-assisted versus video-assisted thoracoscopic oesophagectomy (REVATE trial).The British journal of surgery · 2024Trial
- Clinical factors associated with rescue bronchoscopic sputum suction after minimally invasive esophagectomy: A single-center retrospective study.Surgery today · 2026Article
- Respiratory sarcopenia defined by paraspinal muscle mass and peak expiratory flow predicts postoperative pneumonia after esophagectomy for esophageal cancer: a comparison with sternocleidomastoid muscle mass.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- Article
- How I do it: The Hi-UP approach-single-port da Vinci SP-assisted mediastinoscopic subtotal esophagectomy with a transhiatal-dominant strategy in the abdominal and cervical phases.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- A bibliometric analysis of minimally invasive esophagectomy for esophageal cancer (2005-2024): mapping the knowledge landscape and future trends.Surgical endoscopy · 2026Article
- Position and outcomes of Minimally Invasive transCervical Esophagectomy (MICE) in treatment of esophageal cancer.Journal of thoracic disease · 2026Article
- Comparison of Short-Term Outcomes Between Robot-Assisted and Conventional Mediastinoscopic Esophagectomies: A Retrospective Study Using Propensity Score Matching.Annals of surgical oncology · 2026Article
- Impact of intraoperative nerve integrity monitoring on recurrent laryngeal nerve paralysis in minimally invasive esophagectomy for esophageal cancer: a propensity score-matched analysis.Surgical endoscopy · 2026Article
- Influence of Facility Size on Perioperative Outcomes in Minimally Invasive Esophagectomy for 14 152 Patients With Esophageal Cancer Based on the Japanese National Clinical Database: A Multicenter Cohort Study.Annals of gastroenterological surgery · 2025Article
- The impact of perioperative oral care on postoperative infection in patients with esophageal cancer: a retrospective cohort study before and during COVID-19.Surgery today · 2025Article
- Effect of Intraoperative Posture on Accurate Diagnostic Rate of Intraoperative Nerve Monitoring During Esophagectomy.Annals of gastroenterological surgery · 2025Article
- Effectiveness of recurrent laryngeal nerve monitoring on nerve paralysis during open McKeown esophagectomy: a prospective, cohort study.Langenbeck's archives of surgery · 2025Article
- Risk factors of poor long-term outcomes in elderly patients with esophageal squamous cell carcinoma after minimally invasive esophagectomy.Surgery today · 2025Article
- Comparison of COSurgical endoscopy · 2025Article
- Nomogram for predicting the development of pneumonia after colorectal cancer surgery.Scientific reports · 2025Article
- A nomogram for postoperative pulmonary infections in esophageal cancer patients: a two-center retrospective clinical study.BMC surgery · 2025Article
- Predicting Outcomes in Esophageal Squamous Cell Carcinoma Using scRNA-Seq and Bulk RNA-Seq: A Model Development and Validation Study.Cancer medicine · 2025Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring the past decade, minimally invasive esophagectomy (MIE) for esophageal cancer has been adopted worldwide with expectations of lower invasiveness. However, the rate of postoperative pneumonia, which is an independent risk factor for oncological prognosis in esophageal cancer, remains high. The aim of this retrospective follow-up study is to clarify whether there is a strong correlation between recurrent laryngeal nerve (RLN) palsy and postoperative pneumonia in MIE.
methodsThis retrospective follow-up study included 209 patients with esophageal cancer who underwent thoracoscopic esophagectomy in the prone position (TEP) at Kobe University between 2011 and 2018. Inclusion criteria included age 18-85 years; cT1-3, cN0-3 disease; upper mediastinal lymphadenectomy; and ability to undergo simultaneous esophagectomy and reconstruction of the gastric conduit or pedicled jejunum. Univariate and multivariate logistic regression were conducted to identify independent risk factors for pneumonia.
resultsAmong 209 TEPs, pneumonia of Clavien-Dindo classification grade > II occurred in 44 patients (21%). In the pneumonia positive and negative groups, there were significant differences in age (67.9 ± 7.5 vs. 64.9 ± 8.6 years), 3-field lymph node dissection [27 (61%) vs. 67 (41%)], transfusion [20 (45%) vs. 41 (25%)], left RLN palsy [19 (43%) vs. 18 (11%)], and any RLN palsy [20 (45%) vs. 18 (11%)]. In multivariate analysis, any RLN palsy was associated with a higher incidence of pneumonia [odds ratio (OR), 6.210; 95% confidence interval (CI), 2.728-14.480; P < 0.0001]. In addition, age was associated with a higher incidence of pneumonia (OR, 1.049; 95% CI, 1.001-1.103; P = 0.046). Changes in the rate of any RLN palsy over time were quite similar to changes in the incidence of pneumonia.
conclusionThere is a strong correlation between RLN palsy and pneumonia in MIE for esophageal cancer. Prevention of RLN palsy may reduce the incidence of pneumonia, leading to better oncological prognosis.
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