Evidence map›Paper›PMID 32086501›Full record

ReviewNature reviews. Microbiology2020

Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus.

Matt D Johansen, Jean-Louis Herrmann, Laurent Kremer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 493 papers.

0numbers the graph read from it
0cells of the map it votes in
493citing papers in PubMed
60.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

493 citing papers in PubMed, 773 citations in OpenAlex.

  1. Inflammasomes in respiratory diseases: from disease pathogenesis to drug development and use of multi-omics.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Leucine auxotrophic marker for genetic manipulation ofApplied and environmental microbiology · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Proportions ofJournal of clinical tuberculosis and other mycobacterial diseases · 2026
    Review
  15. Article
  16. Article
  17. Genomic Characterization and Taxonomic Classification ofInternational journal of molecular sciences · 2026
    Article
  18. Article
  19. Article
  20. Article

433 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Matt D JohansenInstitut de Recherche en Infectiologie de Montpellier, Centre National de la Recherche Scientifique UMR 9004, Université de Montpellier, Montpellier, France.ORCID http://orcid.org/0000-0001-5553-5270
Jean-Louis HerrmannUniversité Paris-Saclay, UVSQ, Inserm, Infection et Inflammation, Montigny-Le-Bretonneux, France.
Laurent KremerInstitut de Recherche en Infectiologie de Montpellier, Centre National de la Recherche Scientifique UMR 9004, Université de Montpellier, Montpellier, France. laurent.kremer@irim.cnrs.fr.ORCID http://orcid.org/0000-0002-6604-4458
Inserm · FRUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections caused by non-tuberculous mycobacteria (NTM) are increasing globally and are notoriously difficult to treat due to intrinsic resistance of these bacteria to many common antibiotics. NTM are diverse and ubiquitous in the environment, with only a few species causing serious and often opportunistic infections in humans, including Mycobacterium abscessus. This rapidly growing mycobacterium is one of the most commonly identified NTM species responsible for severe respiratory, skin and mucosal infections in humans. It is often regarded as one of the most antibiotic-resistant mycobacteria, leaving us with few therapeutic options. In this Review, we cover the proposed infection process of M. abscessus, its virulence factors and host interactions and highlight the commonalities and differences of M. abscessus with other NTM species. Finally, we discuss drug resistance mechanisms and future therapeutic options. Taken together, this knowledge is essential to further our understanding of this overlooked and neglected global threat.

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialHumansLung DiseasesMycobacterium abscessusMycobacterium Infections, NontuberculousAnti-Bacterial Agents

Identifiers

PMID32086501
OpenAlexW3009004529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.