Evidence map›Paper›PMID 32086438›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2020

Prolonging gavage feeds for reduction of gastroesophageal reflux in infants.

Michael T Favara, Sheeja Abraham, Joan DiPalma, Michele Epstein, Jay S Greenspan, Zubair H Aghai

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael T FavaraNeonatology/Christiana Care Health System, Newark, DE, 19713, USA.
Sheeja AbrahamPediatric Gastroenterology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
Joan DiPalmaPediatric Gastroenterology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
Michele EpsteinPediatric Gastroenterology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
Jay S GreenspanNeonatology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA.
Zubair H AghaiNeonatology/Thomas Jefferson University/Nemours, Philadelphia, PA, 19107, USA. zaghai@nemours.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if prolonging gavage feedings in infants for ≥60 min is associated with decreased gastroesophageal reflux (GER) compared with bolus feeding using multiple-channel intraluminal impedance with pH probe (MII-pH). STUDY

designRetrospective analysis of infants who underwent MII-pH between October 2009 and July 2018 and received gavage feedings. Infants were divided into two groups: bolus (<30 min) or prolonged (≥60 min). Symptoms, number of reflux events and percent time pH < 4 was compared.

resultFifty-eight infants underwent evaluation. Thirty-one (54%) received bolus gavage feedings and 27 (46%) received prolonged feedings. Groups differed in postmenstrual age. Total reflux episodes were significantly lower with prolonged feeding (median 19 vs. 28 episodes, p = 0.015), with no difference in acid exposure time. There was no significant difference in GER symptoms between the two groups.

conclusionProlongation of gavage feedings was associated with decreased total numbers of GER events without reduction in GER symptoms.

Indexed as

Gastroesophageal RefluxElectric ImpedanceEnteral NutritionHumansHydrogen-Ion ConcentrationInfantRetrospective Studies

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.