Evidence map›Paper›PMID 32086361›Full record

ArticleBMJ open2020

Pharmacist-led intervention to improve medication use in older inpatients using the Drug Burden Index: a study protocol for a before/after intervention with a retrospective control group and multiple case analysis.

Marci Elizabeth Dearing, Susan Bowles, Jennifer Isenor, Olga Kits, Lisa Kouladjian O'Donnell, Heather Neville, Sarah Hilmer, Kent Toombs, Caroline Sirois, Mohammad Hajizadeh and 3 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03698487 (Pharmacist Led Intervention to Improve Medication Use in Older In-patients Living With Frailty), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03698487 naunknown statusnot on this map

Pharmacist Led Intervention to Improve Medication Use in Older In-patients Living With Frailty: the Drug Burden Index

TypeinterventionalSponsorEmilyRan2019 to 2024Enrolled200ConditionsSedative Adverse Reaction, Anticholinergic Adverse ReactionArmsIntervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Marci Elizabeth DearingGeriatric Medicine Research, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.ORCID 0000-0002-6261-2411
Susan BowlesDepartment of Pharmacy, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.ORCID 0000-0003-0821-3222
Jennifer IsenorCollege of Pharmacy, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0003-1648-7362
Olga KitsResearch Methods Unit, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.
Lisa Kouladjian O'DonnellNHMRC Cognitive Decline Partnership Centre, Kolling Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0003-0927-7295
Heather NevilleDepartment of Pharmacy, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.
Sarah HilmerNHMRC Cognitive Decline Partnership Centre, Kolling Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-5970-1501
Kent ToombsDepartment of Pharmacy, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.
Caroline SiroisDepartment of Social and Preventive Medicine, Faculty of Medicine, Universite Laval, Québec city, Quebec, Canada.ORCID 0000-0003-3294-7883
Mohammad HajizadehSchool of Health Administration, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0002-4591-8531
Aprill NegusDepartment of Family Medicine, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.
Kenneth RockwoodGeriatric Medicine Research, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.ORCID 0000-0002-6674-995X
Emily ReeveGeriatric Medicine Research, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada Emily.Reeve@unisa.edu.au.ORCID 0000-0002-1405-999X
Nova Scotia Health Authority · CADalhousie University · CAThe University of Sydney · AUUniversité Laval · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPolypharmacy and potentially inappropriate medication use is common in older adults and is associated with adverse outcomes such as falls and hospitalisations. METHODS AND ANALYSIS: This study is a pharmacist-led medication optimisation initiative using an electronic tool (the Drug Burden Index (DBI) Calculator) in four hospital sites in the Canadian province of Nova Scotia. The study aims to enrol 160 participants between the preintervention and intervention groups. The Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT 2013 checklist) was used to develop the protocol for this prospective interventional implementation study. A preintervention retrospective control cohort and a multiple case study analysis will also be used to assess the effect of intervention implementation. Statistical analysis will involve change in DBI scores and assessment of clinical outcomes, such as rehospitalisation and mortality using appropriate statistical tests including t-test, χ ETHICS AND DISSEMINATION: Ethics approval has been granted by the Nova Scotia Health Authority Research Ethics Board. The findings of this study will be published in peer-reviewed journals and presented at local, national and international conferences. TRIAL REGISTRATION NUMBER: NCT03698487.

Indexed as

Medication AdherencePharmaceutical PreparationsPharmacistsAgedHumansInpatientsMulticenter Studies as TopicNova ScotiaProspective StudiesRandomized Controlled Trials as TopicRetrospective StudiesPharmaceutical Preparationsadverse eventsclinical pharmacologygeriatric medicine

Identifiers

PMID32086361
PMCPMC7044900
OpenAlexW3007657098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.