Evidence map›Paper›PMID 32086277›Full record

ArticleJournal of the American Society of Nephrology : JASN2020

Lydia Hering, Masudur Rahman, Henning Hoch, Lajos Markó, Guang Yang, Annika Reil, Mina Yakoub, Vikram Gupta, Sebastian A Potthoff, Oliver Vonend and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Adrenoceptors and Hypertension.Handbook of experimental pharmacology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Mechanism ofBioMed research international · 2021
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Lydia HeringDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Masudur RahmanDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Henning HochDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Lajos MarkóExperimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max Delbruck Center for Molecular Medicine, Berlin, Germany.
Guang YangDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Annika ReilDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Mina YakoubDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Vikram GuptaDepartment of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
Sebastian A PotthoffDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Oliver VonendDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Donna L RalphDepartment of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California; and.
Susan B GurleyDivision of Nephrology and Hypertension, School of Medicine, Oregon Health and Science University, Portland, Oregon.
Alicia A McDonoughDepartment of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California; and.ORCID 0000-0002-0459-469X
Lars C RumpDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Johannes StegbauerDepartment of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany; johannes.stegbauer@med.uni-duesseldorf.de.
Düsseldorf University Hospital · DEUniversity of Southern California · USMax Delbrück Center · DEOregon Health & Science University · USUniversity of Virginia · USUniversity Town of Shenzhen · CN

Funding

Sodium transporter regulation during hypertensionR01DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AURELIE EDWARDS, Alicia A. McDonough · 2011 to 2026
$5.8M
Actions of Angiotensin II Along the Nephron to Regulate Blood PressureR01DK098382 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GURLEY, SUSAN BAILEY · 2014 to 2025
$3.8M
Sodium-chloride co-transporter regulation in the kidneyR56DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCDONOUGH, ALICIA A., YU, ALAN S · 2010 to 2010
$173k
NIDDK NIH HHS R01 DK083785NIDDK NIH HHS R01 DK098382NIDDK NIH HHS R56 DK083785
6 · The paper itself

Abstract

backgroundIncreased nerve activity causes hypertension and kidney disease. Recent studies suggest that renal denervation reduces BP in patients with hypertension. Renal NE release is regulated by prejunctional

methodsWe investigated effects of

resultsUrinary NE excretion and BP did not differ between normotensive

conclusionsOur findings reveal a protective role of prejunctional inhibitory

Indexed as

Angiotensin IIAnimalsDisease Models, AnimalHypertension, RenalMiceMice, KnockoutNephritisReceptors, Adrenergic, alpha-2SympathectomySympathetic Nervous SystemSynaptic TransmissionAngiotensin IIReceptors, Adrenergic, alpha-2angiotensinchronic kidney diseaseepithelial sodium transporthypertensionrenal sympathetic nervous systemα2-adrenoceptor

Identifiers

PMID32086277
PMCPMC7191918
OpenAlexW3007202809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.