Evidence map›Paper›PMID 32086248›Full record

ArticleG3 (Bethesda, Md.)2020

Identification of Suppressors of

Nirajan Bhandari, Christine Rourke, Thomas Wilmoth, Alekya Bheemreddy, David Schulman, Dina Collins, Harold E Smith, Andy Golden, Aimee Jaramillo-Lambert

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Measuring Embryonic Viability and Brood Size in Caenorhabditis elegans.Journal of visualized experiments : JoVE · 2023
    Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nirajan BhandariDepartment of Biological Sciences, University of Delaware, Newark, Delaware 19701.
Christine RourkeDepartment of Biological Sciences, University of Delaware, Newark, Delaware 19701.ORCID 0000-0002-4585-657X
Thomas WilmothDepartment of Biological Sciences, University of Delaware, Newark, Delaware 19701.
Alekya BheemreddyDepartment of Biological Sciences, University of Delaware, Newark, Delaware 19701.
David SchulmanDepartment of Biological Sciences, University of Delaware, Newark, Delaware 19701.
Dina CollinsDepartment of Biological Sciences, University of Delaware, Newark, Delaware 19701.
Harold E SmithNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
Andy GoldenNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
Aimee Jaramillo-LambertDepartment of Biological Sciences, University of Delaware, Newark, Delaware 19701 anjl@udel.edu.ORCID 0000-0001-7697-8580
University of Delaware · USNational Institutes of Health · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Anjana Narayan Bhat · 2012 to 2026
$67.2M
VOLUMETRIC BREAST DENSITY ESTIMATION USING BREAST SURFACE RECONSTRUCTEDP20RR016472 · NCRR · UNIVERSITY OF DELAWARE · PI STANHOPE, STEVEN J. · 2001 to 2011
$37.6M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Acquisition of a Zeiss LSM710 Confocal MicroscopeS10RR027273 · NCRR · UNIVERSITY OF DELAWARE · PI DUNCAN, MELINDA K · 2010 to 2010
$494k
NCRR NIH HHS P20 RR016472NCRR NIH HHS S10 RR027273NIGMS NIH HHS P20 GM103446NIH HHS P40 OD010440
6 · The paper itself

Abstract

Topoisomerase II is an enzyme with important roles in chromosome biology. This enzyme relieves supercoiling and DNA and RNA entanglements generated during mitosis. Recent studies have demonstrated that Topoisomerase II is also involved in the segregation of homologous chromosomes during the first meiotic division. However, the function and regulation of Topoisomerase II in meiosis has not been fully elucidated. Here, we conducted a genetic suppressor screen in

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAllelesAnimalsMeiosisMitosisCaenorhabditis elegans ProteinsC. elegansmeiosistop-2topoisomerase II

Identifiers

PMID32086248
PMCPMC7144083
OpenAlexW3006726466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.