Evidence map›Paper›PMID 32086169›Full record

ReviewCurrent opinion in chemical biology2020

Bacterial manganese sensing and homeostasis.

Lauren S Waters

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Pleiotropic roles of elongation factor P inMicrobiology spectrum · 2026
    Article
  5. Article
  6. Manganese homeostasis supportsCurrent research in microbial sciences · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Manganese transporters regulate the resumption of replication in hydrogen peroxide-stressed Escherichia coli.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Article
  13. Review
  14. Article
  15. Structural Dynamics of theInternational journal of molecular sciences · 2023
    Article
  16. Article
  17. A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Article
  19. Article
  20. Iron-responsive riboswitches.Current opinion in chemical biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Lauren S WatersDepartment of Chemistry, University of Wisconsin, Oshkosh, WI, 54901, USA. Electronic address: watersl@uwosh.edu.
University of Wisconsin–Oshkosh · US

Funding

Bacterial Manganese HomeostasisR15GM137249 · NIGMS · UNIVERSITY OF WISCONSIN OSHKOSH · PI WATERS, LAUREN · 2020 to 2024
$717k
NIGMS NIH HHS R15 GM137249
6 · The paper itself

Abstract

Manganese (Mn) plays a complex role in the survival of pathogenic and symbiotic bacteria in eukaryotic hosts and is also important for free-living bacteria to thrive in stressful environments. This review summarizes new aspects of regulatory strategies to control intracellular Mn levels and gives an overview of several newly identified families of bacterial Mn transporters. Recent illustrative examples of advances in quantification of intracellular Mn pools and characterization of the effects of Mn perturbations are highlighted. These discoveries help define mechanisms of Mn selectivity and toxicity and could enable new strategies to combat pathogenic bacteria and promote growth of desirable bacteria.

Indexed as

Amino Acid SequenceBacteriaBacterial ProteinsCell Membrane PermeabilityGene Expression Regulation, BacterialHomeostasisManganeseMembrane Transport ProteinsMutationReactive Oxygen SpeciesRiboswitchSubstrate SpecificitySuperoxide DismutaseTranscription FactorsBacterial ProteinsManganeseMembrane Transport ProteinsReactive Oxygen SpeciesRiboswitchSuperoxide DismutaseTranscription FactorsBacteriaManganeseMetal homeostasisMn exportersMn importersMntRyybP-ykoY riboswitch

Identifiers

PMID32086169
PMCPMC9997548
OpenAlexW3007053667

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.