Evidence map›Paper›PMID 32086029›Full record

ArticlePsychiatry research2020

Utilization of the DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure-Adult to Screen Healthy Volunteers for Research Studies.

Margaret Rose Mahoney, Cristan Farmer, Stephen Sinclair, Susanna Sung, Kalene Dehaut, Joyce Y Chung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Examining the factor structure of the DSM-5 Level 1 cross-cutting symptom measure.International journal of methods in psychiatric research · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Margaret Rose MahoneyVanderbilt University School of Medicine, 1161 21st Avenue S Nashville, TN 37232. Electronic address: margaret.r.mahoney@vanderbilt.edu.
Cristan FarmerNational Institute of Mental Health, Office of the Clinical Director, 10 Center Drive, NIH Building 10, Room 6-5340, Bethesda, MD 20892, United States. Electronic address: cristan.farmer@nih.gov.
Stephen SinclairNational Institute of Mental Health, Office of the Clinical Director, 10 Center Drive, NIH Building 10, Room 6-5340, Bethesda, MD 20892, United States. Electronic address: sinclairs2@mail.nih.gov.
Susanna SungNational Institute of Mental Health, Office of the Clinical Director, 10 Center Drive, NIH Building 10, Room 6-5340, Bethesda, MD 20892, United States. Electronic address: sungs@mail.nih.gov.
Kalene DehautNational Institute of Mental Health, Office of the Clinical Director, 10 Center Drive, NIH Building 10, Room 6-5340, Bethesda, MD 20892, United States. Electronic address: kalene.dehaut@nih.gov.
Joyce Y ChungNational Institute of Mental Health, Office of the Clinical Director, 10 Center Drive, NIH Building 10, Room 6-5340, Bethesda, MD 20892, United States. Electronic address: joyce.chung@nih.gov.

Funding

Psychiatry Consultation Liaison Service ResearchZIAMH002922 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PAO, MARYLAND · 2009 to 2025
$11.5M
Intramural NIH HHS Z99 MH999999
6 · The paper itself

Abstract

The DSM-5 Level 1 Cross-Cutting Symptom Measure-Adult (DSM XC) was developed by the American Psychiatric Association (APA) as a transdiagnostic measure of current mental health symptomatology. This paper describes utilization of the DSM XC to screen volunteers for participation in mental health research studies as healthy controls. Research volunteers completed an online, modified version of the DSM XC, which along with other clinical information, was used to determine eligibility for participation as a healthy control. The sensitivity and specificity of screening positive on the DSM XC for this eligibility decision were calculated. Of 506 volunteers who completed the screening process, 159 (31%) were ineligible due to mental health reasons. The DSM XC sensitivity in predicting this determination was 64.2% [95% CI: 56.5 - 71.3] and its specificity was 83.9% [95% CI: 79.7 - 87.5]. When DSM XC responses were combined with information about current psychotropic medication use, an important determinant of study eligibility, the sensitivity improved to 81.8% [95% CI: 75.3 - 87.2). These findings provide preliminary support for the use of the DSM XC as an initial screening tool for mental health studies that enroll healthy research volunteers, particularly when supplemented by additional clinical history such as psychotropic medication use.

Indexed as

Clinical researchMental healthResearch volunteersScreening toolsStudy recruitmentTransdiagnostic

Identifiers

PMID32086029
PMCPMC7382979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.