Evidence map›Paper›PMID 32085642›Full record

ArticleGenes2020

Form from Function, Order from Chaos in Male Germline Chromatin.

Peter J I Ellis, Darren K Griffin

Open access · goldAbstract readEditorial
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Peter J I EllisSchool of Biosciences and Centre for Interdisciplinary Studies of Reproduction, University of Kent, Giles Lane, Canterbury CT2 7NJ, UK.
Darren K GriffinSchool of Biosciences and Centre for Interdisciplinary Studies of Reproduction, University of Kent, Giles Lane, Canterbury CT2 7NJ, UK.
University of Kent · GB

Funding

Biotechnology and Biological Sciences Research Council BB/N000463/1
6 · The paper itself

Abstract

Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving co-ordinated waves of DNA methylation and demethylation, histone modification, replacement and removal occurring before, during and after meiosis. This Special Issue has drawn together papers addressing many aspects of chromatin organization and dynamics in the male germ line, in humans and in model organisms. Two major themes emerge from these studies: the first is the functional significance of nuclear organisation in the developing germline; the second is the interplay between sperm chromatin structure and susceptibility to DNA damage and mutation. The consequences of these aspects for fertility, both in humans and other animals, is a major health and social welfare issue and this is reflected in these nine exciting manuscripts.

Indexed as

SpermatogenesisAnimalsChromatinDNA MethylationHistone CodeHumansMaleMeiosisChromatinassisted reproductionchromatinDNA fragmentationDNA oxidationepigenetic inheritancehistone retentionin vitro fertilisationnuclear organisationspermatogenesis

Identifiers

PMID32085642
PMCPMC7073629
OpenAlexW3008329809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.