Evidence map›Paper›PMID 32085620›Full record

ArticleInternational journal of molecular sciences2020

The Urinary Exosomal miRNA Expression Profile is Predictive of Clinical Response in Lupus Nephritis.

Eloi Garcia-Vives, Cristina Solé, Teresa Moliné, Marta Vidal, Irene Agraz, Josep Ordi-Ros, Josefina Cortés-Hernández

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

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  17. Lupus Nephritis from Pathogenesis to New Therapies: An Update.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Eloi Garcia-VivesVall d'Hebron University Hospital, Vall d'Hebron Research Insitute (VHIR), Rheumatology Research Group, Lupus Unit, 08035 Barcelona, Spain.
Cristina SoléVall d'Hebron University Hospital, Vall d'Hebron Research Insitute (VHIR), Rheumatology Research Group, Lupus Unit, 08035 Barcelona, Spain.ORCID 0000-0002-4870-2824
Teresa MolinéVall d'Hebron University Hospital, Department of Renal Pathology, 08035 Barcelona, Spain.
Marta VidalParc Taulí Foundation-UAB University Institute, Department of Renal Pathology, 08208 Barcelona, Spain.
Irene AgrazVall d'Hebron University Hospital, Department of Nephrology, 08035 Barcelona, Spain.ORCID 0000-0002-4223-6834
Josep Ordi-RosVall d'Hebron University Hospital, Department of Internal Medicine, 08035 Barcelona, Spain.
Josefina Cortés-HernándezVall d'Hebron University Hospital, Vall d'Hebron Research Insitute (VHIR), Rheumatology Research Group, Lupus Unit, 08035 Barcelona, Spain.
Hebron University · PS

Funding

A.Bosch Foundation 2015-2018Catalan Lupus Foundation 2015-2018Instituto de Salud Carlos III PI15/02117
6 · The paper itself

Abstract

Data on exosomal-derived urinary miRNAs have identified several miRNAs associated with disease activity and fibrosis formation, but studies on prognosis are lacking. We conducted a qPCR array screening on urinary exosomes from 14 patients with biopsy-proven proliferative lupus glomerulonephritis with a renal outcome of clinical response (

Indexed as

Gene Expression ProfilingAdultCohort StudiesCytokinesEndocytosisEndothelial CellsExosomesFemaleGene Expression RegulationHumansHypoxia-Inducible Factor 1, alpha SubunitInflammationInflammation MediatorsKidney TubulesLupus NephritisMaleCytokinesHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitInflammation MediatorsMicroRNAsbiomarkerslupus nephritisresponsetherapyurinary exosomes

Identifiers

PMID32085620
PMCPMC7073236
OpenAlexW3008613171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.