Evidence map›Paper›PMID 32085478›Full record

ReviewInternational journal of molecular sciences2020

Bioinformatics Approaches to the Understanding of Molecular Mechanisms in Antimicrobial Resistance.

Pieter-Jan Van Camp, David B Haslam, Aleksey Porollo

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Microbiology (Reading, England) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Secondary analysis ofmicroPublication biology · 2024
    Article
  13. Review
  14. Article
  15. Antibiotic-ResistantVeterinary sciences · 2022
    Article
  16. Role of Efflux Pumps on Antimicrobial Resistance inInternational journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pieter-Jan Van CampDepartment of Biomedical Informatics, University of Cincinnati, Cincinnati, OH 45267, USA.
David B HaslamDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Aleksey PorolloDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-3202-5099

Funding

Copper tolerance and homeostasis in Pneumocystis speciesR21AI143467 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI POROLLO, ALEXEY · 2019 to 2020
$454k
Academic Research Committee at Cincinnati Children's Hospital Medical Center 53561CDC HHS OADS BAA 2016-N-17812National Institute of Allergy and Infectious Diseases R21-AI143467NIAID NIH HHS R21 AI143467
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a major health concern worldwide. A better understanding of the underlying molecular mechanisms is needed. Advances in whole genome sequencing and other high-throughput unbiased instrumental technologies to study the molecular pathogenicity of infectious diseases enable the accumulation of large amounts of data that are amenable to bioinformatic analysis and the discovery of new signatures of AMR. In this work, we review representative methods published in the past five years to define major approaches developed to-date in the understanding of AMR mechanisms. Advantages and limitations for applications of these methods in clinical laboratory testing and basic research are discussed.

Indexed as

AnimalsAnti-Bacterial AgentsComputational BiologyDrug Resistance, BacterialGene Expression Regulation, BacterialHumansMetabolomicsAnti-Bacterial Agentsantibiotic resistance genesantimicrobial resistancebioinformatic analysismolecular mechanismsprediction of antibiotic resistance

Identifiers

PMID32085478
PMCPMC7072858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.